Ruxolitinib Methyl ester impurity

About Ruxolitinib Methyl ester impurity

Ruxolitinib Methyl ester impurity is an impurity of Ruxolitinib carrying the CAS registry number 2950130-23-9. With the molecular formula C18H21N5O2, it has a molar mass of 339.4 g/mol. The IUPAC name is methyl (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanoate. Common synonyms include Methyl.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Ruxolitinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Ruxolitinib Methyl ester impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ruxolitinib Methyl ester impurity
Catalogue No.	VQ-033711
CAS Number	2950130-23-9
IUPAC name	methyl (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanoate
Molecular formula	C₁₈H₂₁N₅O₂
Molecular weight	339.4 g/mol
Exact mass	339.1695
Grade	Reference Standard
HSN code	38229090
InChIKey	MZJMLSFSOSUEKH-OAHLLOKOSA-N
SMILES	COC(=O)C[C@H](C1CCCC1)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
PubChem CID	168449881

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 5
TPSA	85.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ruxolitinib Methyl ester impurity?

The CAS Registry Number of Ruxolitinib Methyl ester impurity is 2950130-23-9. It is also known as Methyl, Methyl (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoate.

What is the molecular formula and molecular weight of Ruxolitinib Methyl ester impurity?

Ruxolitinib Methyl ester impurity has the molecular formula C18H21N5O2 and a molecular weight of 339.4 g/mol. Its IUPAC name is methyl (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanoate.

What is Ruxolitinib Methyl ester impurity used for?

Ruxolitinib Methyl ester impurity is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ruxolitinib Methyl ester impurity can I order?

We supply Ruxolitinib Methyl ester impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ruxolitinib Methyl ester impurity?

Yes. Every lot of Ruxolitinib Methyl ester impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ruxolitinib Methyl ester impurity be shipped internationally?

Yes. We export Ruxolitinib Methyl ester impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.