Liothyronine EP Impurity B (Freebase)

Name: Liothyronine EP Impurity B (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-006489

About Liothyronine EP Impurity B (Freebase)

Listed under CAS 300-39-0, Liothyronine EP Impurity B (Freebase) is a pharmacopeial impurity of Liothyronine available from Vaqora Chemicals. With the molecular formula C9H9I2NO3, it has a molar mass of 432.98 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid. Common synonyms include 3',5'-Diiodo-L-tyrosine and Bijodtyrosin.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Liothyronine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Liothyronine

View every impurity, metabolite and intermediate we list for Liothyronine.

Liothyronine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Liothyronine EP Impurity B (Freebase)
Catalogue No.	VQ-006489
CAS Number	300-39-0
IUPAC name	(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
Molecular formula	C₉H₉I₂NO₃
Molecular weight	432.98 g/mol
Exact mass	432.8672
Grade	Reference Standard
HSN code	38229090
InChIKey	NYPYHUZRZVSYKL-ZETCQYMHSA-N
SMILES	C1=C(C=C(C(=C1I)O)I)C[C@@H](C(=O)O)N
PubChem CID	9305

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	3 / 4
TPSA	83.6 Å²
Synonyms	(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic Acid, 3',5'-Diiodo-L-tyrosine, Bijodtyrosin, L-3,5-Diiodotyrosine, 3,5-Diiodo-L-tyrosine, L-Diiodotyrosine, L-Tyrosine, 3,5-diiodo-, Tyrosine, 3,5-diiodo-, L-, (2S)-2-azaniumyl-3-(4-hydroxy-3,5-diiodophenyl)propanoate, Diiodotyrosine, H-Tyr(3,5-I2)-OH, 3,5-L-Diiodotyrosine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Liothyronine EP Impurity B (Freebase)?

The CAS Registry Number of Liothyronine EP Impurity B (Freebase) is 300-39-0. It is also known as (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic Acid, 3',5'-Diiodo-L-tyrosine, Bijodtyrosin.

What is the molecular formula and molecular weight of Liothyronine EP Impurity B (Freebase)?

Liothyronine EP Impurity B (Freebase) has the molecular formula C9H9I2NO3 and a molecular weight of 432.98 g/mol. Its IUPAC name is (2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid.

What is Liothyronine EP Impurity B (Freebase) used for?

Liothyronine EP Impurity B (Freebase) is supplied as a characterised reference material related to Liothyronine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Liothyronine EP Impurity B (Freebase) can I order?

We supply Liothyronine EP Impurity B (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Liothyronine EP Impurity B (Freebase)?

Yes. Every lot of Liothyronine EP Impurity B (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Liothyronine EP Impurity B (Freebase) be shipped internationally?

Yes. Liothyronine EP Impurity B (Freebase) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.