Cefazolin EP Impurity A

Name: Cefazolin EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-021086

About Cefazolin EP Impurity A

Listed under CAS 30246-33-4, Cefazolin EP Impurity A is a pharmacopeial impurity of Cefazolin available from Vaqora Chemicals. With the molecular formula C11H12N4O3S3, it has a molar mass of 344.4 g/mol. It is also known as Cefazolin Sodium - Impurity A or 7-ZACA.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Cefazolin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cefazolin EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cefazolin

View every impurity, metabolite and intermediate we list for Cefazolin.

Cefazolin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cefazolin EP Impurity A
Catalogue No.	VQ-021086
CAS Number	30246-33-4
IUPAC name	(6R,7R)-7-amino-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular formula	C₁₁H₁₂N₄O₃S₃
Molecular weight	344.4 g/mol
Exact mass	344.0072
Grade	Reference Standard
HSN code	38229090
InChIKey	HJSGHKMSDOLGJJ-HZGVNTEJSA-N
SMILES	CC1=NN=C(S1)SCC2=C(N3[C@@H]([C@@H](C3=O)N)SC2)C(=O)O
PubChem CID	6350581

Physical properties
Physical form	Solid
LogP (XLogP3)	-3.2
H-bond donors / acceptors	2 / 9
TPSA	188 Å²
Synonyms	Cefazolin Sodium - Impurity A, 7-ZACA, 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid, 7-TDA, 7beta-amino-3-(2-methyl-1,3,4-thiadiazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid, 7beta-amino-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements: P233, P260, P261, P264, P264 + P265, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P342 + P316, P362 + P364, P403, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cefazolin EP Impurity A?

The CAS Registry Number of Cefazolin EP Impurity A is 30246-33-4. It is also known as Cefazolin Sodium - Impurity A, 7-ZACA, 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid.

What is the molecular formula and molecular weight of Cefazolin EP Impurity A?

Cefazolin EP Impurity A has the molecular formula C11H12N4O3S3 and a molecular weight of 344.4 g/mol. Its IUPAC name is (6R,7R)-7-amino-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

What is Cefazolin EP Impurity A used for?

Cefazolin EP Impurity A is supplied as a characterised reference material related to Cefazolin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cefazolin EP Impurity A can I order?

We supply Cefazolin EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cefazolin EP Impurity A?

Yes. Every lot of Cefazolin EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cefazolin EP Impurity A be shipped internationally?

Yes. Cefazolin EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.