2-(tert-Butoxycarbonylamino)thiazole-5-carbox… 302964-02-9

Name: 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-012919

About 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid

2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid (CAS 302964-02-9) is a process intermediate or related compound of Dasatinib offered by Vaqora Chemicals. Formula C9H12N2O4S, molecular weight 244.27 g/mol. Its systematic (IUPAC) name is 2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazole-5-carboxylic acid. It is also known as 2-Boc-Aminothiazole-5-carboxylic acid or 2-N-Boc-aminothiazole-5-carboxylic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Dasatinib, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dasatinib

View every impurity, metabolite and intermediate we list for Dasatinib.

Dasatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid
Catalogue No.	VQ-012919
CAS Number	302964-02-9
IUPAC name	2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazole-5-carboxylic acid
Molecular formula	C₉H₁₂N₂O₄S
Molecular weight	244.27 g/mol
Exact mass	244.0518
Grade	Reference Standard
HSN code	2933
InChIKey	QNFLEDLPOVONCN-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)NC1=NC=C(S1)C(=O)O
PubChem CID	22271442

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	2 / 6
TPSA	117 Å²
Synonyms	2-Boc-Aminothiazole-5-carboxylic acid, 2-N-Boc-aminothiazole-5-carboxylic acid, 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-thiazolecarboxylic acid, 2-N-Boc-Amino-thiazole-5-carboxylic acid, 2-[(tert-butoxycarbonyl)amino]-1,3-thiazole-5-carboxylic acid, 2-(n-boc)-aminothiazole-5-carboxylic acid, 2-(Boc-amino)thiazole-5-carboxylic Acid, 2-((tert-butoxycarbonyl)amino)thiazole-5-carboxylic acid, 2-{[(tert-butoxy)carbonyl]amino}-1,3-thiazole-5-carboxylic acid, 2-N-Boc-amino-thiazole-5-carboxylic acid, AldrichCPR, 2-Boc-Aminothiazole-5-carboxylicacid, 2-amino-1,3-thiazole-5-carboxylic acid, n-boc

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements: P261, P272, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid?

The CAS Registry Number of 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid is 302964-02-9. It is also known as 2-Boc-Aminothiazole-5-carboxylic acid, 2-N-Boc-aminothiazole-5-carboxylic acid, 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-thiazolecarboxylic acid.

What is the molecular formula and molecular weight of 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid?

2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid has the molecular formula C9H12N2O4S and a molecular weight of 244.27 g/mol. Its IUPAC name is 2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-thiazole-5-carboxylic acid.

What is 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid used for?

2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid is supplied as a characterised reference material related to Dasatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid can I order?

We supply 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid?

Yes. Every lot of 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid be shipped internationally?

Yes. 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.