2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazol… 302964-24-5

About 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide

2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide is a process intermediate or related compound of Dasatinib carrying the CAS registry number 302964-24-5. Formula C11H10ClN3OS, molecular weight 267.74 g/mol. Its systematic (IUPAC) name is 2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Dasatinib, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dasatinib

View every impurity, metabolite and intermediate we list for Dasatinib.

Dasatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide
Catalogue No.	VQ-012932
CAS Number	302964-24-5
IUPAC name	2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide
Molecular formula	C₁₁H₁₀ClN₃OS
Molecular weight	267.74 g/mol
Exact mass	267.0233
Grade	Reference Standard
HSN code	2933
InChIKey	VVOXTERFTAJMAA-UHFFFAOYSA-N
SMILES	CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)N
PubChem CID	21911644

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 4
TPSA	96.3 Å²
Synonyms	2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide, 5-Thiazolecarboxamide, 2-amino-N-(2-chloro-6-methylphenyl)-, 2-Amino-N-(2-chloro-6-methylphenyl)thiazole -5-carboxamide, 2-amino-N-(2-chloro-6-methyl-phenyl)thiazole-5-carboxamide, 2-amino-N-(2-chloro-6-methyl phenyl)-5-thiazole carboxamide

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H317May cause an allergic skin reaction
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P264, P270, P272, P273, P280, P301 + P316, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide?

The CAS Registry Number of 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide is 302964-24-5. It is also known as 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide, 5-Thiazolecarboxamide, 2-amino-N-(2-chloro-6-methylphenyl)-, 2-Amino-N-(2-chloro-6-methylphenyl)thiazole -5-carboxamide.

What is the molecular formula and molecular weight of 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide?

2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide has the molecular formula C11H10ClN3OS and a molecular weight of 267.74 g/mol. Its IUPAC name is 2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide.

What is 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide used for?

2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide is supplied as a characterised reference material related to Dasatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide can I order?

We supply 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide?

Yes. Every lot of 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide be shipped internationally?

Yes. 2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.