N-Nitroso-L-Hydroxyproline
Synonyms: N-Nitroso (2S,4R)-4-Hydroxypyrrolidin-2-Carboxylic acid · N-Nitrosohydroxyproline · (4R)-4-hydroxy-1-nitroso-L-proline · trans-4-Hydroxy-1-nitroso-L-proline
N-Nitroso-L-Hydroxyproline (CAS 30310-80-6) – nitrosamine impurity reference standard. C5H8N2O4, MW 160.13. Vaqora Chemicals: COA, global shipping.
About N-Nitroso-L-Hydroxyproline
Vaqora Chemicals supplies N-Nitroso-L-Hydroxyproline, a nitrosamine impurity of Hydroxyproline registered under CAS number 30310-80-6. Its molecular formula is C5H8N2O4 and its molecular weight is 160.13 g/mol. Systematically, it is named (2S,4R)-4-hydroxy-1-nitrosopyrrolidine-2-carboxylic acid. It is also known as N-Nitrosohydroxyproline or (4R)-4-hydroxy-1-nitroso-L-proline.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.
It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Hydroxyproline, method validation (AMV) and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies N-Nitroso-L-Hydroxyproline in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.
Typical applications
- Nitrosamine risk assessment
- Trace LC-MS/MS quantitation
- Method validation (AMV)
- Regulatory submissions
Industries
View every impurity, metabolite and intermediate we list for Hydroxyproline.
Hydroxyproline impuritiesSpecifications & identifiers
| Product name | N-Nitroso-L-Hydroxyproline |
|---|---|
| Catalogue No. | VQ-027126 |
| CAS Number | 30310-80-6 |
| IUPAC name | (2S,4R)-4-hydroxy-1-nitrosopyrrolidine-2-carboxylic acid |
| Molecular formula | C5H8N2O4 |
| Molecular weight | 160.13 g/mol |
| Exact mass | 160.0484 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | ABVBOWJCKJGCJM-DMTCNVIQSA-N |
| SMILES | C1[C@H](CN([C@@H]1C(=O)O)N=O)O |
| PubChem CID | 61873 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | -0.7 |
| H-bond donors / acceptors | 2 / 6 |
| TPSA | 90.2 Ų |
| Synonyms | N-Nitroso (2S,4R)-4-Hydroxypyrrolidin-2-Carboxylic acid, N-Nitrosohydroxyproline, (4R)-4-hydroxy-1-nitroso-L-proline, trans-4-Hydroxy-1-nitroso-L-proline, Proline, 4-hydroxy-1-nitroso-, L-, 4-Hydroxy-1-nitroso-L-proline, Nitrosohydroxyproline, L-Proline, 4-hydroxy-1-nitroso-, (4R)-, (2S,4R)-4-hydroxy-1-nitroso-pyrrolidine-2-carboxylic acid |
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Frequently asked questions
What is the CAS number of N-Nitroso-L-Hydroxyproline?
The CAS Registry Number of N-Nitroso-L-Hydroxyproline is 30310-80-6. It is also known as N-Nitroso (2S,4R)-4-Hydroxypyrrolidin-2-Carboxylic acid, N-Nitrosohydroxyproline, (4R)-4-hydroxy-1-nitroso-L-proline.
What is the molecular formula and molecular weight of N-Nitroso-L-Hydroxyproline?
N-Nitroso-L-Hydroxyproline has the molecular formula C5H8N2O4 and a molecular weight of 160.13 g/mol. Its IUPAC name is (2S,4R)-4-hydroxy-1-nitrosopyrrolidine-2-carboxylic acid.
What is N-Nitroso-L-Hydroxyproline used for?
N-Nitroso-L-Hydroxyproline is supplied as a characterised reference material related to Hydroxyproline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of N-Nitroso-L-Hydroxyproline can I order?
We supply N-Nitroso-L-Hydroxyproline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with N-Nitroso-L-Hydroxyproline?
Yes. Every lot of N-Nitroso-L-Hydroxyproline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can N-Nitroso-L-Hydroxyproline be shipped internationally?
Yes. We export N-Nitroso-L-Hydroxyproline worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about N-Nitroso-L-Hydroxyproline
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