Tizanidine EP Impurity E

Name: Tizanidine EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-023907

About Tizanidine EP Impurity E

Listed under CAS 30536-19-7, Tizanidine EP Impurity E is a pharmacopeial impurity of Tizanidine available from Vaqora Chemicals. The compound has the formula C6H4ClN3S, corresponding to a molecular weight of 185.64 g/mol. The IUPAC name is 5-chloro-2,1,3-benzothiadiazol-4-amine. It is also known as 4-Amino-5-chloro-2,1,3-benzothiadiazole or Tizanidine Hydrochloride - Impurity E.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Tizanidine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tizanidine EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Tizanidine

View every impurity, metabolite and intermediate we list for Tizanidine.

Tizanidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tizanidine EP Impurity E
Catalogue No.	VQ-023907
CAS Number	30536-19-7
IUPAC name	5-chloro-2,1,3-benzothiadiazol-4-amine
Molecular formula	C₆H₄ClN₃S
Molecular weight	185.64 g/mol
Exact mass	184.9814
Grade	Reference Standard
HSN code	38229090
InChIKey	MURNIACGGUSMAP-UHFFFAOYSA-N
SMILES	C1=CC2=NSN=C2C(=C1Cl)N
PubChem CID	771620

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 4
TPSA	80 Å²
Synonyms	4-Amino-5-chloro-2,1,3-benzothiadiazole, Tizanidine Hydrochloride - Impurity E, 2,1,3-Benzothiadiazol-4-amine, 5-chloro-, 5-Chlorobenzo[c][1,2,5]thiadiazol-4-amine, 4-Amino-5-chloropiazthiole, 5-Chloro-benzo[1,2,5]thiadiazol-4-ylamine, 5-Chloro-2,1,3-benzothiadiazol-4-amine, AldrichCPR, 5-chlorobenzo[c]1,2,5-thiadiazole-4-ylamine, 5-Chloro-2,1,3-benzothiadiazol-4-amine (4-Amino-5-chloro-2,1,3-benzothiadiazole), 5-Chlorobenzo[1,2,5]thiadiazol-4-ylamine

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P264 + P265, P273, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tizanidine EP Impurity E?

The CAS Registry Number of Tizanidine EP Impurity E is 30536-19-7. It is also known as 4-Amino-5-chloro-2,1,3-benzothiadiazole, Tizanidine Hydrochloride - Impurity E, 2,1,3-Benzothiadiazol-4-amine, 5-chloro-.

What is the molecular formula and molecular weight of Tizanidine EP Impurity E?

Tizanidine EP Impurity E has the molecular formula C6H4ClN3S and a molecular weight of 185.64 g/mol. Its IUPAC name is 5-chloro-2,1,3-benzothiadiazol-4-amine.

What is Tizanidine EP Impurity E used for?

Tizanidine EP Impurity E is supplied as a characterised reference material related to Tizanidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tizanidine EP Impurity E can I order?

We supply Tizanidine EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tizanidine EP Impurity E?

Yes. Every lot of Tizanidine EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tizanidine EP Impurity E be shipped internationally?

Yes. Tizanidine EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.