2-C-Methyluridine

Name: 2-C-Methyluridine
Brand: Vaqora Chemicals
SKU: VQ-039820

About 2-C-Methyluridine

Vaqora Chemicals supplies 2-C-Methyluridine, an impurity of Sofosbuvir registered under CAS number 31448-54-1. With the molecular formula C10H14N2O6, it has a molar mass of 258.23 g/mol. Systematically, it is named 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione. Alternative names: Uridine, 2'-C-methyl- and 2'-Methyl Uridine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Sofosbuvir, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-C-Methyluridine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sofosbuvir

View every impurity, metabolite and intermediate we list for Sofosbuvir.

Sofosbuvir impurities

Specifications & identifiers

Chemical identifiers
Product name	2-C-Methyluridine
Catalogue No.	VQ-039820
CAS Number	31448-54-1
IUPAC name	1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione
Molecular formula	C₁₀H₁₄N₂O₆
Molecular weight	258.23 g/mol
Exact mass	258.0852
Grade	Reference Standard
HSN code	38229090
InChIKey	NBKORJKMMVZAOZ-VPCXQMTMSA-N
SMILES	C[C@]1([C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O)O
PubChem CID	500903

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.1
H-bond donors / acceptors	4 / 6
TPSA	119 Å²
Synonyms	Uridine, 2'-C-methyl-, 2'-Methyl Uridine, 2'-C-Methyl-D-uridine, BCX-4018, 1-(2-C-Methyl--D-ribofuranosyl)uracil, 1-(2-C-Methyl-, A-D-ribofuranosyl)uracil, 2,4(1H,3H)-pyrimidinedione, 1-(2-C-methyl-.beta.-D-ribofuranosyl)-

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H371May cause damage to organs

Precautionary statements: P260, P264, P270, P308 + P316, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-C-Methyluridine?

The CAS Registry Number of 2-C-Methyluridine is 31448-54-1. It is also known as Uridine, 2'-C-methyl-, 2'-Methyl Uridine, 2'-C-Methyl-D-uridine.

What is the molecular formula and molecular weight of 2-C-Methyluridine?

2-C-Methyluridine has the molecular formula C10H14N2O6 and a molecular weight of 258.23 g/mol. Its IUPAC name is 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione.

What is 2-C-Methyluridine used for?

2-C-Methyluridine is supplied as a characterised reference material related to Sofosbuvir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-C-Methyluridine can I order?

We supply 2-C-Methyluridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-C-Methyluridine?

Yes. Every lot of 2-C-Methyluridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-C-Methyluridine be shipped internationally?

Yes. 2-C-Methyluridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.