N-Nitroso-Loperamide EP Impurity C

About N-Nitroso-Loperamide EP Impurity C

N-Nitroso-Loperamide EP Impurity C is a nitrosamine impurity of Haloperidol carrying the CAS registry number 3192-36-7. With the molecular formula C11H13ClN2O2, it has a molar mass of 240.68 g/mol. The IUPAC name is 4-(4-chlorophenyl)-1-nitrosopiperidin-4-ol. It is also known as Haloperidol nitroso Impurity 53.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitroso-Loperamide EP Impurity C in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Haloperidol

View every impurity, metabolite and intermediate we list for Haloperidol.

Haloperidol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-Loperamide EP Impurity C
Catalogue No.	VQ-026497
CAS Number	3192-36-7
IUPAC name	4-(4-chlorophenyl)-1-nitrosopiperidin-4-ol
Molecular formula	C₁₁H₁₃ClN₂O₂
Molecular weight	240.68 g/mol
Exact mass	240.0666
Grade	Reference Standard
HSN code	38229090
InChIKey	IHXJUMJVTANEEJ-UHFFFAOYSA-N
SMILES	C1CN(CCC1(C2=CC=C(C=C2)Cl)O)N=O
PubChem CID	119089663

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 4
TPSA	52.9 Å²

Safety & hazard information (GHS)

Explosive

Flammable

Harmful / irritant

Signal word: Danger

Hazard statements

H241Heating may cause a fire or explosion
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P210, P234, P235, P240, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P380 + P375, P378, P403

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-Loperamide EP Impurity C?

The CAS Registry Number of N-Nitroso-Loperamide EP Impurity C is 3192-36-7. It is also known as Haloperidol nitroso Impurity 53.

What is the molecular formula and molecular weight of N-Nitroso-Loperamide EP Impurity C?

N-Nitroso-Loperamide EP Impurity C has the molecular formula C11H13ClN2O2 and a molecular weight of 240.68 g/mol. Its IUPAC name is 4-(4-chlorophenyl)-1-nitrosopiperidin-4-ol.

What is N-Nitroso-Loperamide EP Impurity C used for?

N-Nitroso-Loperamide EP Impurity C is supplied as a characterised reference material related to Haloperidol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-Loperamide EP Impurity C can I order?

We supply N-Nitroso-Loperamide EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-Loperamide EP Impurity C?

Yes. Every lot of N-Nitroso-Loperamide EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-Loperamide EP Impurity C be shipped internationally?

Yes. N-Nitroso-Loperamide EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.