2-Nitro-4-(trifluoromethyl)benzoic Acid

Name: 2-Nitro-4-(trifluoromethyl)benzoic Acid
Brand: Vaqora Chemicals
SKU: VQ-032188

About 2-Nitro-4-(trifluoromethyl)benzoic Acid

2-Nitro-4-(trifluoromethyl)benzoic Acid is an impurity of Nitisinone carrying the CAS registry number 320-94-5. With the molecular formula C8H4F3NO4, it has a molar mass of 235.12 g/mol. Common synonyms include 4-(trifluoromethyl)-2-nitrobenzoic acid and benzoic acid, 2-nitro-4-(trifluoromethyl)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Nitisinone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Nitro-4-(trifluoromethyl)benzoic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nitisinone

View every impurity, metabolite and intermediate we list for Nitisinone.

Nitisinone impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Nitro-4-(trifluoromethyl)benzoic Acid
Catalogue No.	VQ-032188
CAS Number	320-94-5
IUPAC name	2-nitro-4-(trifluoromethyl)benzoic acid
Molecular formula	C₈H₄F₃NO₄
Molecular weight	235.12 g/mol
Exact mass	235.0092
Grade	Reference Standard
HSN code	38229090
InChIKey	MYSAXQPTXWKDPQ-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1C(F)(F)F)[N+](=O)[O-])C(=O)O
PubChem CID	642096

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 7
TPSA	83.1 Å²
Synonyms	4-(trifluoromethyl)-2-nitrobenzoic acid, alpha,alpha,alpha-Trifluoro-2-nitro-p-toluic acid, p-Toluic acid, alpha,alpha,alpha-trifluoro-2-nitro-, benzoic acid, 2-nitro-4-(trifluoromethyl)-, 4-trifluoromethyl-2-nitrobenzoic acid, 2-Nitro-alpha,alpha,alpha-trifluor-p-toluic acid, 2-nitro-4-triflouromethyl-benzoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Nitro-4-(trifluoromethyl)benzoic Acid?

The CAS Registry Number of 2-Nitro-4-(trifluoromethyl)benzoic Acid is 320-94-5. It is also known as 4-(trifluoromethyl)-2-nitrobenzoic acid, alpha,alpha,alpha-Trifluoro-2-nitro-p-toluic acid, p-Toluic acid, alpha,alpha,alpha-trifluoro-2-nitro-.

What is the molecular formula and molecular weight of 2-Nitro-4-(trifluoromethyl)benzoic Acid?

2-Nitro-4-(trifluoromethyl)benzoic Acid has the molecular formula C8H4F3NO4 and a molecular weight of 235.12 g/mol. Its IUPAC name is 2-nitro-4-(trifluoromethyl)benzoic acid.

What is 2-Nitro-4-(trifluoromethyl)benzoic Acid used for?

2-Nitro-4-(trifluoromethyl)benzoic Acid is supplied as a characterised reference material related to Nitisinone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Nitro-4-(trifluoromethyl)benzoic Acid can I order?

We supply 2-Nitro-4-(trifluoromethyl)benzoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Nitro-4-(trifluoromethyl)benzoic Acid?

Yes. Every lot of 2-Nitro-4-(trifluoromethyl)benzoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Nitro-4-(trifluoromethyl)benzoic Acid be shipped internationally?

Yes. 2-Nitro-4-(trifluoromethyl)benzoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.