Diltiazem Hydrochloride

Name: Diltiazem Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007428

About Diltiazem Hydrochloride

Vaqora Chemicals supplies Diltiazem Hydrochloride, a high-purity reference standard of Diltiazem registered under CAS number 33286-22-5. The compound has the formula C22H27ClN2O4S, corresponding to a molecular weight of 451.0 g/mol. Common synonyms include (S,S)-Diltiazem hydrochloride and (2S,3S)-(+)-cis-Diltiazem hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Diltiazem standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Specifications & identifiers

Chemical identifiers
Product name	Diltiazem Hydrochloride
Catalogue No.	VQ-007428
CAS Number	33286-22-5
Other CAS	42399-41-7, 139492-78-7
IUPAC name	[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride
Molecular formula	C₂₂H₂₇ClN₂O₄S
Molecular weight	451 g/mol
Exact mass	450.138
Grade	Reference Standard
HSN code	38229090
InChIKey	HDRXZJPWHTXQRI-BHDTVMLSSA-N
SMILES	CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl
PubChem CID	62920

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 6
TPSA	84.4 Å²
Synonyms	(S,S)-Diltiazem hydrochloride, (2S,3S)-(+)-cis-Diltiazem hydrochloride, (+)-Diltiazem hydrochloride, d-cis-Diltiazem hydrochloride, Adizem, Altiazem, Anginyl, Angipress, Angizem, Bi-Teldiem, Blocalcin 60, Britiazim

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diltiazem Hydrochloride?

The CAS Registry Number of Diltiazem Hydrochloride is 33286-22-5. It is also known as (S,S)-Diltiazem hydrochloride, (2S,3S)-(+)-cis-Diltiazem hydrochloride, (+)-Diltiazem hydrochloride.

What is the molecular formula and molecular weight of Diltiazem Hydrochloride?

Diltiazem Hydrochloride has the molecular formula C22H27ClN2O4S and a molecular weight of 451 g/mol.

What is Diltiazem Hydrochloride used for?

Diltiazem Hydrochloride is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diltiazem Hydrochloride can I order?

We supply Diltiazem Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diltiazem Hydrochloride?

Yes. Every lot of Diltiazem Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diltiazem Hydrochloride be shipped internationally?

Yes. Diltiazem Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.