Rhein 8-Glucoside

Name: Rhein 8-Glucoside
Brand: Vaqora Chemicals
SKU: VQ-040102

About Rhein 8-Glucoside

Vaqora Chemicals supplies Rhein 8-Glucoside, an impurity of Sennoside registered under CAS number 34298-86-7. Formula C21H18O11, molecular weight 446.4 g/mol. Alternative names: Rhein 8-O-beta-D-Glucopyranoside and rhein 8-O-beta-D-glucoside.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Sennoside, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sennoside

View every impurity, metabolite and intermediate we list for Sennoside.

Sennoside impurities

Specifications & identifiers

Chemical identifiers
Product name	Rhein 8-Glucoside
Catalogue No.	VQ-040102
CAS Number	34298-86-7
IUPAC name	4-hydroxy-9,10-dioxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-2-carboxylic acid
Molecular formula	C₂₁H₁₈O₁₁
Molecular weight	446.4 g/mol
Exact mass	446.0849
Grade	Reference Standard
HSN code	38229090
InChIKey	WYKUTTFFZMQCGO-HTRBZNBPSA-N
SMILES	C1=CC2=C(C(=C1)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C(=O)C4=C(C2=O)C=C(C=C4O)C(=O)O
PubChem CID	5320961

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	6 / 11
TPSA	191 Å²
Synonyms	Rhein 8-O-beta-D-Glucopyranoside, 2-Anthracenecarboxylic acid,5-(b-D-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-, rhein 8-O-beta-D-glucoside, rhein-8-O-beta-D-glucoside, Rhein 8-O-, A-D-Glucopyranoside, rhein 5-O-beta-D-glucopyranoside, Rhein 8-O-I(2)-D-glucopyranoside, 5-(beta-D-Glucopyranosyloxy)-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rhein 8-Glucoside?

The CAS Registry Number of Rhein 8-Glucoside is 34298-86-7. It is also known as Rhein 8-O-beta-D-Glucopyranoside, 2-Anthracenecarboxylic acid,5-(b-D-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-, rhein 8-O-beta-D-glucoside.

What is the molecular formula and molecular weight of Rhein 8-Glucoside?

Rhein 8-Glucoside has the molecular formula C21H18O11 and a molecular weight of 446.4 g/mol. Its IUPAC name is 4-hydroxy-9,10-dioxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-2-carboxylic acid.

What is Rhein 8-Glucoside used for?

Rhein 8-Glucoside is supplied as a characterised reference material related to Sennoside. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rhein 8-Glucoside can I order?

We supply Rhein 8-Glucoside in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rhein 8-Glucoside?

Yes. Every lot of Rhein 8-Glucoside is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rhein 8-Glucoside be shipped internationally?

Yes. Rhein 8-Glucoside is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.