Cetirizine EP Impurity D

Name: Cetirizine EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-006297

About Cetirizine EP Impurity D

Cetirizine EP Impurity D (CAS 346451-15-8) is a pharmacopeial impurity of Cetirizine offered by Vaqora Chemicals. Formula C30H28Cl2N2, molecular weight 487.5 g/mol. Its systematic (IUPAC) name is 1,4-bis[(4-chlorophenyl)-phenylmethyl]piperazine. Common synonyms include Cetirizine Impurity D and Cetirizine dimer.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

This Cetirizine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Cetirizine EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cetirizine

View every impurity, metabolite and intermediate we list for Cetirizine.

Cetirizine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cetirizine EP Impurity D
Catalogue No.	VQ-006297
CAS Number	346451-15-8
Other CAS	856841-95-7
IUPAC name	1,4-bis[(4-chlorophenyl)-phenylmethyl]piperazine
Molecular formula	C₃₀H₂₈Cl₂N₂
Molecular weight	487.5 g/mol
Exact mass	486.163
Grade	Reference Standard
HSN code	38229090
InChIKey	ZHKWYPRSELVIIG-UHFFFAOYSA-N
SMILES	C1CN(CCN1C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl)C(C4=CC=CC=C4)C5=CC=C(C=C5)Cl
PubChem CID	413327

Physical properties
Physical form	Solid
LogP (XLogP3)	7.7
H-bond donors / acceptors	0 / 2
TPSA	6.5 Å²
Synonyms	1,4-bis((4-chlorophenyl)phenylmethyl)Piperazine, Cetirizine Impurity D, 1,4-bis[(4-chlorophenyl)phenylmethyl]piperazine, 1,4-bis((4-chlorophenyl)(phenyl)methyl)piperazine, 1,4-bis[(4-chlorophenyl)(phenyl)methyl]piperazine, Cetirizine dimer, Piperazine, 1,4-bis((4-chlorophenyl)phenylmethyl)-, 1,4-bis(4-Chlorobenzhydryl)piperazine, 1,4-bis-(4-chlorobenzhydryl)piperazine, 1,4-bis-[(4-chlorophenyl)phenylmethyl]piperazine, 1,4-bis[(4-chlorophenyl)-phenyl-methyl]piperazine, Cetirizine EP Impurity D

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H400Very toxic to aquatic life

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cetirizine EP Impurity D?

The CAS Registry Number of Cetirizine EP Impurity D is 346451-15-8. It is also known as 1,4-bis((4-chlorophenyl)phenylmethyl)Piperazine, Cetirizine Impurity D, 1,4-bis[(4-chlorophenyl)phenylmethyl]piperazine.

What is the molecular formula and molecular weight of Cetirizine EP Impurity D?

Cetirizine EP Impurity D has the molecular formula C30H28Cl2N2 and a molecular weight of 487.5 g/mol. Its IUPAC name is 1,4-bis[(4-chlorophenyl)-phenylmethyl]piperazine.

What is Cetirizine EP Impurity D used for?

Cetirizine EP Impurity D is supplied as a characterised reference material related to Cetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cetirizine EP Impurity D can I order?

We supply Cetirizine EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cetirizine EP Impurity D?

Yes. Every lot of Cetirizine EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cetirizine EP Impurity D be shipped internationally?

Yes. Cetirizine EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.