Cotinine-d4

Name: Cotinine-d4
Brand: Vaqora Chemicals
SKU: VQ-049237

About Cotinine-d4

Vaqora Chemicals supplies Cotinine-d4, a stable isotope labelled analogue related to Nicotine Hemisulfate registered under CAS number 350818-68-7. With the molecular formula C10H12N2O, it has a molar mass of 180.24 g/mol. Systematically, it is named 1-methyl-5-(2,4,5,6-tetradeuterio-3-pyridinyl)pyrrolidin-2-one. Alternative names: (Rac)-Cotinine-d4 and (+/-)-Cotinine-d4 (pyridine-d4).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Cotinine-d4 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Nicotine Hemisulfate

View every impurity, metabolite and intermediate we list for Nicotine Hemisulfate.

Nicotine Hemisulfate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cotinine-d4
Catalogue No.	VQ-049237
CAS Number	350818-68-7
IUPAC name	1-methyl-5-(2,4,5,6-tetradeuterio-3-pyridinyl)pyrrolidin-2-one
Molecular formula	C₁₀H₁₂N₂O
Molecular weight	180.24 g/mol
Exact mass	180.1201
Grade	Reference Standard
HSN code	38229090
InChIKey	UIKROCXWUNQSPJ-USSMZTJJSA-N
SMILES	[2H]C1=C(C(=C(N=C1[2H])[2H])C2CCC(=O)N2C)[2H]
PubChem CID	76973746

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	0 / 2
TPSA	33.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cotinine-d4?

The CAS Registry Number of Cotinine-d4 is 350818-68-7. It is also known as (Rac)-Cotinine-d4, (+/-)-Cotinine-d4 (pyridine-d4), (+/-)-Cotinine-2,4,5,6-d4 (pyridine-d4).

What is the molecular formula and molecular weight of Cotinine-d4?

Cotinine-d4 has the molecular formula C10H12N2O and a molecular weight of 180.24 g/mol. Its IUPAC name is 1-methyl-5-(2,4,5,6-tetradeuterio-3-pyridinyl)pyrrolidin-2-one.

What is Cotinine-d4 used for?

Cotinine-d4 is supplied as a characterised reference material related to Nicotine Hemisulfate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cotinine-d4 can I order?

We supply Cotinine-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cotinine-d4?

Yes. Every lot of Cotinine-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cotinine-d4 be shipped internationally?

Yes. We export Cotinine-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.