Pemetrexed Disodium 2.5 Hydrate

Name: Pemetrexed Disodium 2.5 Hydrate
Brand: Vaqora Chemicals
SKU: VQ-041378

About Pemetrexed Disodium 2.5 Hydrate

Vaqora Chemicals supplies Pemetrexed Disodium 2.5 Hydrate, a process intermediate or related compound of Pemetrexed registered under CAS number 357166-30-4. Formula C40H48N10Na4O17, molecular weight 1032.8 g/mol. Common synonyms include Pemetrexed Disodium Hemipentahydrate and Pemetrexed sodium hydrate (2:4:5).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Pemetrexed, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Pemetrexed Disodium 2.5 Hydrate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Pemetrexed

View every impurity, metabolite and intermediate we list for Pemetrexed.

Pemetrexed impurities

Specifications & identifiers

Chemical identifiers
Product name	Pemetrexed Disodium 2.5 Hydrate
Catalogue No.	VQ-041378
CAS Number	357166-30-4
IUPAC name	tetrasodium;bis((2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate);pentahydrate
Molecular formula	C₄₀H₄₈N₁₀Na₄O₁₇
Molecular weight	1032.8 g/mol
Exact mass	1032.279
HSN code	2933
InChIKey	ZCTCZKWJFTYNMZ-WKUCUCPSSA-J
SMILES	C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Na+].[Na+].[Na+].[Na+]
PubChem CID	135564527

Physical properties
Physical form	Solid
H-bond donors / acceptors	13 / 19
TPSA	390 Å²
Synonyms	Pemetrexed Disodium Hemipentahydrate, Pemetrexed sodium hydrate (2:4:5), Pemetrexed accord, Pemetrexed disodium hydrate, Pemetrexed disodium hemipenta hydrate, Pemetrexed sodium hemipentahydrate (JAN), Pemetrexed sodium hy, Disodium Salt Heptahydrate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P264 + P265, P270, P280, P302 + P352, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pemetrexed Disodium 2.5 Hydrate?

The CAS Registry Number of Pemetrexed Disodium 2.5 Hydrate is 357166-30-4. It is also known as Pemetrexed Disodium Hemipentahydrate, Pemetrexed sodium hydrate (2:4:5), Pemetrexed accord.

What is the molecular formula and molecular weight of Pemetrexed Disodium 2.5 Hydrate?

Pemetrexed Disodium 2.5 Hydrate has the molecular formula C40H48N10Na4O17 and a molecular weight of 1032.8 g/mol.

What is Pemetrexed Disodium 2.5 Hydrate used for?

Pemetrexed Disodium 2.5 Hydrate is supplied as a characterised reference material related to Pemetrexed. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pemetrexed Disodium 2.5 Hydrate can I order?

We supply Pemetrexed Disodium 2.5 Hydrate, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pemetrexed Disodium 2.5 Hydrate?

Yes. Every lot of Pemetrexed Disodium 2.5 Hydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pemetrexed Disodium 2.5 Hydrate be shipped internationally?

Yes. Pemetrexed Disodium 2.5 Hydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.