Dinoprostone EP Impurity C (Free Base)

About Dinoprostone EP Impurity C (Free Base)

Dinoprostone EP Impurity C (Free Base) is a pharmacopeial impurity of Alprostadil carrying the CAS registry number 36150-00-2. The compound has the formula C20H32O5, corresponding to a molecular weight of 352.5 g/mol. Systematically, it is named (E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid. It is also known as Alprostadil - Impurity H or Dinoprostone EP Impurity C.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Alprostadil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Dinoprostone EP Impurity C (Free Base) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Alprostadil

View every impurity, metabolite and intermediate we list for Alprostadil.

Alprostadil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dinoprostone EP Impurity C (Free Base)
Catalogue No.	VQ-021516
CAS Number	36150-00-2
IUPAC name	(E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
Molecular formula	C₂₀H₃₂O₅
Molecular weight	352.5 g/mol
Exact mass	352.225
Grade	Reference Standard
HSN code	38229090
InChIKey	XEYBRNLFEZDVAW-BRNHSORCSA-N
SMILES	CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C/CCCC(=O)O)O)O
PubChem CID	5283116

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	3 / 5
TPSA	94.8 Å²
Synonyms	Alprostadil - Impurity H, Dinoprostone EP Impurity C, Alprostadil EP Impurity H, Dinoprostone - Impurity C, 5-trans-Prostaglandin E2, trans-Dinoprostone, 5-trans-PGE2, 5,6-trans-PGE2, 5,6-trans-Dinoprostone, Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5E,11alpha,13E,15S)-, 9-oxo-11R,15S-dihydroxy-5E,13E-prostadienoic acid, Alprostadil impurity H

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dinoprostone EP Impurity C (Free Base)?

The CAS Registry Number of Dinoprostone EP Impurity C (Free Base) is 36150-00-2. It is also known as Alprostadil - Impurity H, Dinoprostone EP Impurity C, Alprostadil EP Impurity H.

What is the molecular formula and molecular weight of Dinoprostone EP Impurity C (Free Base)?

Dinoprostone EP Impurity C (Free Base) has the molecular formula C20H32O5 and a molecular weight of 352.5 g/mol. Its IUPAC name is (E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid.

What is Dinoprostone EP Impurity C (Free Base) used for?

Dinoprostone EP Impurity C (Free Base) is supplied as a characterised reference material related to Alprostadil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dinoprostone EP Impurity C (Free Base) can I order?

We supply Dinoprostone EP Impurity C (Free Base) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dinoprostone EP Impurity C (Free Base)?

Yes. Every lot of Dinoprostone EP Impurity C (Free Base) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dinoprostone EP Impurity C (Free Base) be shipped internationally?

Yes. Dinoprostone EP Impurity C (Free Base) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.