Silybin

Name: Silybin
Brand: Vaqora Chemicals
SKU: VQ-039080

About Silybin

Silybin (CAS 36804-17-8) is a high-purity reference standard of Silybin offered by Vaqora Chemicals. With the molecular formula C25H22O10, it has a molar mass of 482.4 g/mol. Common synonyms include Silibin and Silybin (Mixture of Diastereomers).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Silybin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Silybin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Silybin

View every impurity, metabolite and intermediate we list for Silybin.

Silybin impurities

Specifications & identifiers

Chemical identifiers
Product name	Silybin
Catalogue No.	VQ-039080
CAS Number	36804-17-8
IUPAC name	(2R,3R)-3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
Molecular formula	C₂₅H₂₂O₁₀
Molecular weight	482.4 g/mol
Exact mass	482.1213
Grade	Reference Standard
HSN code	38229090
InChIKey	SEBFKMXJBCUCAI-DBMPWETRSA-N
SMILES	COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
PubChem CID	3086637

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	5 / 10
TPSA	155 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Silybin?

The CAS Registry Number of Silybin is 36804-17-8. It is also known as Silibin, Silybin (Mixture of Diastereomers).

What is the molecular formula and molecular weight of Silybin?

Silybin has the molecular formula C25H22O10 and a molecular weight of 482.4 g/mol. Its IUPAC name is (2R,3R)-3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one.

What is Silybin used for?

Silybin is supplied as a characterised reference material related to Silybin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Silybin can I order?

We supply Silybin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Silybin?

Yes. Every lot of Silybin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Silybin be shipped internationally?

Yes. Silybin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.