Chlorhexidine Dihydrochloride

Name: Chlorhexidine Dihydrochloride
Brand: Vaqora Chemicals
SKU: VQ-029743

About Chlorhexidine Dihydrochloride

Listed under CAS 3697-42-5, Chlorhexidine Dihydrochloride is a high-purity reference standard of Chlorhexidine available from Vaqora Chemicals. With the molecular formula C22H32Cl4N10, it has a molar mass of 578.4 g/mol. Alternative names: Chlorhexidine HCl and Dantroche hibitane.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Chlorhexidine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Chlorhexidine Dihydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Chlorhexidine

View every impurity, metabolite and intermediate we list for Chlorhexidine.

Chlorhexidine impurities

Specifications & identifiers

Chemical identifiers
Product name	Chlorhexidine Dihydrochloride
Catalogue No.	VQ-029743
CAS Number	3697-42-5
IUPAC name	(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;dihydrochloride
Molecular formula	C₂₂H₃₂Cl₄N₁₀
Molecular weight	578.4 g/mol
Exact mass	578.1536
Grade	Reference Standard
HSN code	38229090
InChIKey	WJLVQTJZDCGNJN-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1N/C(=N/C(=NCCCCCCN=C(/N=C(/NC2=CC=C(C=C2)Cl)\N)N)N)/N)Cl.Cl.Cl
PubChem CID	9571016

Physical properties
Physical form	Solid
H-bond donors / acceptors	8 / 2
TPSA	178 Å²
Synonyms	Chlorhexidine HCl, Dantroche hibitane, Chlorhex hcl, 1,1'-Hexamethylenebis(5-(4-chlorophenyl)biguanide) dihydrochloride, 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] Dihydrochloride, Nolvasan Cap-Tabs, Nolvasan Suspension, Hydrochloride, Chlorhexidine, Chlorhexidine 2HCl, Arlacide H, Chlorhexidinium dichloride

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P261, P264, P264 + P265, P271, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Chlorhexidine Dihydrochloride?

The CAS Registry Number of Chlorhexidine Dihydrochloride is 3697-42-5. It is also known as Chlorhexidine HCl, Dantroche hibitane, Chlorhex hcl.

What is the molecular formula and molecular weight of Chlorhexidine Dihydrochloride?

Chlorhexidine Dihydrochloride has the molecular formula C22H32Cl4N10 and a molecular weight of 578.4 g/mol.

What is Chlorhexidine Dihydrochloride used for?

Chlorhexidine Dihydrochloride is supplied as a characterised reference material related to Chlorhexidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlorhexidine Dihydrochloride can I order?

We supply Chlorhexidine Dihydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlorhexidine Dihydrochloride?

Yes. Every lot of Chlorhexidine Dihydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlorhexidine Dihydrochloride be shipped internationally?

Yes. Chlorhexidine Dihydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.