Ethylene-D4-diamine

About Ethylene-D4-diamine

Ethylene-D4-diamine is a stable isotope labelled analogue related to Amine carrying the CAS registry number 37164-19-5. The compound has the formula C2H8N2, corresponding to a molecular weight of 64.12 g/mol. Its systematic (IUPAC) name is 1,1,2,2-tetradeuterioethane-1,2-diamine. Alternative names: 1,2-Ethane-1,1,2,2-d4-diamine and 1,2-(2H4)Ethanediamine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Amine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Amine

View every impurity, metabolite and intermediate we list for Amine.

Amine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ethylene-D4-diamine
Catalogue No.	VQ-041132
CAS Number	37164-19-5
IUPAC name	1,1,2,2-tetradeuterioethane-1,2-diamine
Molecular formula	C₂H₈N₂
Molecular weight	64.12 g/mol
Exact mass	64.0939
Grade	Reference Standard
HSN code	38229090
InChIKey	PIICEJLVQHRZGT-LNLMKGTHSA-N
SMILES	[2H]C([2H])(C([2H])([2H])N)N
PubChem CID	12200820

Physical properties
Physical form	Solid
LogP (XLogP3)	-2
H-bond donors / acceptors	2 / 2
TPSA	52 Å²

Safety & hazard information (GHS)

Flammable

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H226Flammable liquid and vapor
H302+H312Harmful if swallowed or in contact with skin
H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P303 + P361 + P353, P304 + P340, P305 + P354 + P338, P316, P317, P321

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethylene-D4-diamine?

The CAS Registry Number of Ethylene-D4-diamine is 37164-19-5. It is also known as 1,2-Ethane-1,1,2,2-d4-diamine, 1,2-(2H4)Ethanediamine, (~2~H_4_)Ethane-1,2-diamine.

What is the molecular formula and molecular weight of Ethylene-D4-diamine?

Ethylene-D4-diamine has the molecular formula C2H8N2 and a molecular weight of 64.12 g/mol. Its IUPAC name is 1,1,2,2-tetradeuterioethane-1,2-diamine.

What is Ethylene-D4-diamine used for?

Ethylene-D4-diamine is supplied as a characterised reference material related to Amine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethylene-D4-diamine can I order?

We supply Ethylene-D4-diamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethylene-D4-diamine?

Yes. Every lot of Ethylene-D4-diamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethylene-D4-diamine be shipped internationally?

Yes. Ethylene-D4-diamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.