(1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-… 376608-70-7

About (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride

(1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride is an impurity of Ticagrelor carrying the CAS registry number 376608-70-7. Its molecular formula is C10H7ClF2O and its molecular weight is 216.61 g/mol. Its systematic (IUPAC) name is trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carbonyl chloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Ticagrelor impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	(1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride
Catalogue No.	VQ-044301
CAS Number	376608-70-7
IUPAC name	trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carbonyl chloride
Molecular formula	C₁₀H₇ClF₂O
Molecular weight	216.61 g/mol
Exact mass	216.0153
Grade	Reference Standard
HSN code	38229090
InChIKey	VSBZGERVJAWYAP-NKWVEPMBSA-N
SMILES	C1[C@H]([C@@H]1C(=O)Cl)C2=CC(=C(C=C2)F)F
PubChem CID	9813209

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 3
TPSA	17.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride?

The CAS Registry Number of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride is 376608-70-7. It is also known as (1R,2R)-2-(3,4-difluorophenyl)-1-cyclopropanecarbonyl chloride.

What is the molecular formula and molecular weight of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride?

(1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride has the molecular formula C10H7ClF2O and a molecular weight of 216.61 g/mol. Its IUPAC name is trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carbonyl chloride.

What is (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride used for?

(1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride can I order?

We supply (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride?

Yes. Every lot of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride be shipped internationally?

Yes. We export (1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.