- CAS
- 1643378-48-6
- Formula
- C23H28F2N6O4S
- MW
- 522.6 g/mol
Ticagrelor Related Compound A
Synonyms: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-hydroxy(phenyl)ethanoate · Ticagrelor EP Impurity E Maleate · Ticagrelor impurity E (2R)-Hydroxy(phenyl)ethanoate salt · Ticagrelor impurity E with alpha-R-hydroxy-Benzeneacetic acid salt
Ticagrelor Related Compound A (CAS 376608-71-8) – Ticagrelor impurity standard. C17H17F2NO3, MW 321.32. Request a quote: COA, bulk packs and worldwide export.
About Ticagrelor Related Compound A
Ticagrelor Related Compound A is a metabolite or degradation product of Ticagrelor carrying the CAS registry number 376608-71-8. With the molecular formula C17H17F2NO3, it has a molar mass of 321.32 g/mol. Common synonyms include Ticagrelor EP Impurity E Maleate and Ticagrelor Impurity 128.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.
Analytical teams use this compound to identify metabolites and degradants of Ticagrelor, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ticagrelor Related Compound A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Industries
View every impurity, metabolite and intermediate we list for Ticagrelor.
Ticagrelor impuritiesSpecifications & identifiers
| Product name | Ticagrelor Related Compound A |
|---|---|
| Catalogue No. | VQ-028366 |
| CAS Number | 376608-71-8 |
| IUPAC name | (2R)-2-hydroxy-2-phenylacetic acid;trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine |
| Molecular formula | C17H17F2NO3 |
| Molecular weight | 321.32 g/mol |
| Exact mass | 321.1176 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | GUESUQPLVFMJIT-KLTOLQSASA-N |
| SMILES | C1[C@H]([C@@H]1N)C2=CC(=C(C=C2)F)F.C1=CC=C(C=C1)[C@H](C(=O)O)O |
| PubChem CID | 9944965 |
| Physical form | Solid |
|---|---|
| H-bond donors / acceptors | 3 / 6 |
| TPSA | 83.6 Ų |
| Synonyms | (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-hydroxy(phenyl)ethanoate, Ticagrelor EP Impurity E Maleate, Ticagrelor impurity E (2R)-Hydroxy(phenyl)ethanoate salt, Ticagrelor impurity E with alpha-R-hydroxy-Benzeneacetic acid salt, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate, Ticagrelor Impurity 128, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine R-mandelate, (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine (2R)-2-hydroxy-2-phenylacetic acid, (1R,2S)-2-(3,4-Difluorophenyl) cyclopropanaminium (2R)-hydroxy(phenyl)ethanoat, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetic acid, CS-M1881, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (R)-Mandelate |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H315Causes skin irritationH319Causes serious eye irritation
Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Ticagrelor Related Compound A?
The CAS Registry Number of Ticagrelor Related Compound A is 376608-71-8. It is also known as (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-hydroxy(phenyl)ethanoate, Ticagrelor EP Impurity E Maleate, Ticagrelor impurity E (2R)-Hydroxy(phenyl)ethanoate salt.
What is the molecular formula and molecular weight of Ticagrelor Related Compound A?
Ticagrelor Related Compound A has the molecular formula C17H17F2NO3 and a molecular weight of 321.32 g/mol.
What is Ticagrelor Related Compound A used for?
Ticagrelor Related Compound A is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Ticagrelor Related Compound A can I order?
We supply Ticagrelor Related Compound A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Ticagrelor Related Compound A?
Yes. Every lot of Ticagrelor Related Compound A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Ticagrelor Related Compound A be shipped internationally?
Yes. Ticagrelor Related Compound A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Ticagrelor Related Compound A
We reply within one business day with price, pack options, lead time and documentation.
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- CAS
- 2056269-94-2
- Formula
- C23H28F2N6O4S
- MW
- 522.6 g/mol