4-Oxo-all-trans Retinoic Acid

Name: 4-Oxo-all-trans Retinoic Acid
Brand: Vaqora Chemicals
SKU: VQ-026244

About 4-Oxo-all-trans Retinoic Acid

Listed under CAS 38030-57-8, 4-Oxo-all-trans Retinoic Acid is a metabolite or degradation product of Isotretinoin available from Vaqora Chemicals. The compound has the formula C20H26O3, corresponding to a molecular weight of 314.4 g/mol. The IUPAC name is (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid. It is also known as 4-Oxoretinoic Acid or 4-Ketoretinoic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Isotretinoin, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Oxo-all-trans Retinoic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Oxo-all-trans Retinoic Acid
Catalogue No.	VQ-026244
CAS Number	38030-57-8
IUPAC name	(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
Molecular formula	C₂₀H₂₆O₃
Molecular weight	314.4 g/mol
Exact mass	314.1882
Grade	Reference Standard
HSN code	38229090
InChIKey	GGCUJPCCTQNTJF-FRCNGJHJSA-N
SMILES	CC1=C(C(CCC1=O)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C
PubChem CID	6437063

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²
Synonyms	4-Oxoretinoic Acid, 4-Ketoretinoic acid, all-trans-4-Oxo-retinoic acid, Retinoic acid, 4-oxo-, all-trans-4-oxoretinoic acid, all-trans 4-Keto Retinoic Acid, 4-Oxotretinoin, 4-oxo-Retinoic acid, 4-Oxo-atRA, 4-keto-Retinoic acid

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Oxo-all-trans Retinoic Acid?

The CAS Registry Number of 4-Oxo-all-trans Retinoic Acid is 38030-57-8. It is also known as 4-Oxoretinoic Acid, 4-Ketoretinoic acid, all-trans-4-Oxo-retinoic acid.

What is the molecular formula and molecular weight of 4-Oxo-all-trans Retinoic Acid?

4-Oxo-all-trans Retinoic Acid has the molecular formula C20H26O3 and a molecular weight of 314.4 g/mol. Its IUPAC name is (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid.

What is 4-Oxo-all-trans Retinoic Acid used for?

4-Oxo-all-trans Retinoic Acid is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Oxo-all-trans Retinoic Acid can I order?

We supply 4-Oxo-all-trans Retinoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Oxo-all-trans Retinoic Acid?

Yes. Every lot of 4-Oxo-all-trans Retinoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Oxo-all-trans Retinoic Acid be shipped internationally?

Yes. 4-Oxo-all-trans Retinoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.