4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dim… 380843-12-9

About 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile

4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile is an impurity of Bosutinib carrying the CAS registry number 380843-12-9. The compound has the formula C19H15Cl2N3O3, corresponding to a molecular weight of 404.2 g/mol. Its systematic (IUPAC) name is 4-(2,4-dichloro-5-methoxyanilino)-6,7-dimethoxyquinoline-3-carbonitrile.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Bosutinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bosutinib

View every impurity, metabolite and intermediate we list for Bosutinib.

Bosutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile
Catalogue No.	VQ-024626
CAS Number	380843-12-9
IUPAC name	4-(2,4-dichloro-5-methoxyanilino)-6,7-dimethoxyquinoline-3-carbonitrile
Molecular formula	C₁₉H₁₅Cl₂N₃O₃
Molecular weight	404.2 g/mol
Exact mass	403.049
Grade	Reference Standard
HSN code	38229090
InChIKey	VPAAYYSCJUHANG-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=C(C=C3Cl)Cl)OC)OC
PubChem CID	5328917

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	1 / 6
TPSA	76.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile?

The CAS Registry Number of 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile is 380843-12-9. It is also known as 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile, Des(4-methyl-1-piperazinyl)propyl Methyl Bosutinib, 4-Phenylamino-3-quinolinecarbonitrile deriv. 1c.

What is the molecular formula and molecular weight of 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile?

4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile has the molecular formula C19H15Cl2N3O3 and a molecular weight of 404.2 g/mol. Its IUPAC name is 4-(2,4-dichloro-5-methoxyanilino)-6,7-dimethoxyquinoline-3-carbonitrile.

What is 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile used for?

4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile is supplied as a characterised reference material related to Bosutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile can I order?

We supply 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile?

Yes. Every lot of 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile be shipped internationally?

Yes. We export 4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.