1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone

Name: 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone
Brand: Vaqora Chemicals
SKU: VQ-027438

About 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone

1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone (CAS 381725-50-4) is an impurity of Perampanel offered by Vaqora Chemicals. Its molecular formula is C16H12N2O and its molecular weight is 248.28 g/mol. Its systematic (IUPAC) name is 1-phenyl-5-pyridin-2-ylpyridin-2-one. It is also known as 1'-Phenyl-[2,3'-bipyridin]-6'(1'H)-one or 1`-phenyl-[2,3`-bipyridin]-6`(1`H)-one.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Perampanel, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Perampanel

View every impurity, metabolite and intermediate we list for Perampanel.

Perampanel impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone
Catalogue No.	VQ-027438
CAS Number	381725-50-4
IUPAC name	1-phenyl-5-pyridin-2-ylpyridin-2-one
Molecular formula	C₁₆H₁₂N₂O
Molecular weight	248.28 g/mol
Exact mass	248.095
Grade	Reference Standard
HSN code	38229090
InChIKey	JHBMGQOABUXDND-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)N2C=C(C=CC2=O)C3=CC=CC=N3
PubChem CID	20872595

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 2
TPSA	33.2 Å²
Synonyms	1'-Phenyl-[2,3'-bipyridin]-6'(1'H)-one, 1`-phenyl-[2,3`-bipyridin]-6`(1`H)-one, 1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one, 1'-Phenyl[2,3'-bipyridin]-6'(1'H)-one, [2,3'-Bipyridin]-6'(1'H)-one, 1'-phenyl-, Perampanel Intermediate 2, 1-phenyl-5-(2-pyridyl)pyridin-2-one, 5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one, 5-(2-Pyridyl)-1-phenyl-1,2-dihydropyridine-2-one, 1'-phenyl-1',6'-dihydro-[2,3'-bipyridine]-6'-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H335May cause respiratory irritation

Precautionary statements: P261, P271, P304 + P340, P319, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone?

The CAS Registry Number of 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone is 381725-50-4. It is also known as 1'-Phenyl-[2,3'-bipyridin]-6'(1'H)-one, 1`-phenyl-[2,3`-bipyridin]-6`(1`H)-one, 1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one.

What is the molecular formula and molecular weight of 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone?

1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone has the molecular formula C16H12N2O and a molecular weight of 248.28 g/mol. Its IUPAC name is 1-phenyl-5-pyridin-2-ylpyridin-2-one.

What is 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone used for?

1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone is supplied as a characterised reference material related to Perampanel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone can I order?

We supply 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone?

Yes. Every lot of 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone be shipped internationally?

Yes. 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.