4-Phenoxyphthalonitrile

Name: 4-Phenoxyphthalonitrile
Brand: Vaqora Chemicals
SKU: VQ-004299

About 4-Phenoxyphthalonitrile

4-Phenoxyphthalonitrile (CAS 38791-62-7) is an impurity of Ruxolitinib offered by Vaqora Chemicals, specified at 99.96% purity. Its molecular formula is C14H8N2O and its molecular weight is 220.23 g/mol. Systematically, it is named 4-phenoxybenzene-1,2-dicarbonitrile. It is also known as ROX8 Regio Isomer (Stage-1) or 4-Phenoxy-1,2-benzenedicarbonitrile.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

This Ruxolitinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Phenoxyphthalonitrile
Catalogue No.	VQ-004299
CAS Number	38791-62-7
IUPAC name	4-phenoxybenzene-1,2-dicarbonitrile
Molecular formula	C₁₄H₈N₂O
Molecular weight	220.23 g/mol
Exact mass	220.0637
Grade	Reference Standard
Purity / assay	99.96%
HSN code	38229090
InChIKey	CRZSSXUMRNESCC-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)OC2=CC(=C(C=C2)C#N)C#N
PubChem CID	371800

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 3
TPSA	56.8 Å²
Synonyms	ROX8 Regio Isomer (Stage-1), 4-Phenoxy-1,2-benzenedicarbonitrile, 1,2-Dicyano-4-phenoxybenzene, 4-phenoxy-phthalonitrile, 1,2-Benzenedicarbonitrile, 4-phenoxy-, 4-Phenoxybenzene-1,2-dinitrile, 4-Phenoxyphthalonitrile, 98%, ROXA-013, RSYYCyclobenzaprine hydrochloride)-5

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Phenoxyphthalonitrile?

The CAS Registry Number of 4-Phenoxyphthalonitrile is 38791-62-7. It is also known as ROX8 Regio Isomer (Stage-1), 4-Phenoxy-1,2-benzenedicarbonitrile, 1,2-Dicyano-4-phenoxybenzene.

What is the molecular formula and molecular weight of 4-Phenoxyphthalonitrile?

4-Phenoxyphthalonitrile has the molecular formula C14H8N2O and a molecular weight of 220.23 g/mol. Its IUPAC name is 4-phenoxybenzene-1,2-dicarbonitrile.

What is 4-Phenoxyphthalonitrile used for?

4-Phenoxyphthalonitrile is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Phenoxyphthalonitrile can I order?

We supply 4-Phenoxyphthalonitrile in Reference Standard (99.96%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Phenoxyphthalonitrile?

Yes. Every lot of 4-Phenoxyphthalonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Phenoxyphthalonitrile be shipped internationally?

Yes. 4-Phenoxyphthalonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.