Estradiol Acetate

Name: Estradiol Acetate
Brand: Vaqora Chemicals
SKU: VQ-030570

About Estradiol Acetate

Listed under CAS 4245-41-4, Estradiol Acetate is a high-purity reference standard of Estradiol available from Vaqora Chemicals. The compound has the formula C20H26O3, corresponding to a molecular weight of 314.4 g/mol. Common synonyms include Estradiol-3-Acetate and Estradiol 3-acetate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Estradiol, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	Estradiol Acetate
Catalogue No.	VQ-030570
CAS Number	4245-41-4
IUPAC name	[(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] acetate
Molecular formula	C₂₀H₂₆O₃
Molecular weight	314.4 g/mol
Exact mass	314.1882
Grade	Reference Standard
HSN code	38229090
InChIKey	FHXBMXJMKMWVRG-SLHNCBLASA-N
SMILES	CC(=O)OC1=CC2=C(C=C1)[C@H]3CC[C@]4([C@H]([C@@H]3CC2)CC[C@@H]4O)C
PubChem CID	9818306

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²
Synonyms	Estradiol-3-Acetate, Estradiol 3-acetate, 3-O-Acetylestradiol, 17beta-Estradiol 3-acetate, Estradiol, 3-acetate, beta-Estradiol 3-acetate, E 3A, 3-Acetoxyestra-1,3,5(10)-trien-17beta-ol, 17beta-Hydroxy-3-acetoxyestra-1,3,5(10)-triene, 17beta-Hydroxyestra-1,3,5(10)-trien-3-yl acetate, Estra-1,3,5(10)-triene-3,17beta-diyl 3-acetate

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Estradiol Acetate?

The CAS Registry Number of Estradiol Acetate is 4245-41-4. It is also known as Estradiol-3-Acetate, Estradiol 3-acetate, 3-O-Acetylestradiol.

What is the molecular formula and molecular weight of Estradiol Acetate?

Estradiol Acetate has the molecular formula C20H26O3 and a molecular weight of 314.4 g/mol. Its IUPAC name is [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] acetate.

What is Estradiol Acetate used for?

Estradiol Acetate is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Estradiol Acetate can I order?

We supply Estradiol Acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Estradiol Acetate?

Yes. Every lot of Estradiol Acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Estradiol Acetate be shipped internationally?

Yes. Estradiol Acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.