Midodrine

Name: Midodrine
Brand: Vaqora Chemicals
SKU: VQ-031890

About Midodrine

Midodrine (CAS 42794-76-3) is a high-purity reference standard of Midodrine offered by Vaqora Chemicals. With the molecular formula C12H18N2O4, it has a molar mass of 254.28 g/mol. The IUPAC name is 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide. It is also known as Midodrin or Midodrine free base.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

As a reference sample of Midodrine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Midodrine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Midodrine

View every impurity, metabolite and intermediate we list for Midodrine.

Midodrine impurities

Specifications & identifiers

Chemical identifiers
Product name	Midodrine
Catalogue No.	VQ-031890
CAS Number	42794-76-3
IUPAC name	2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide
Molecular formula	C₁₂H₁₈N₂O₄
Molecular weight	254.28 g/mol
Exact mass	254.1267
Grade	Reference Standard
HSN code	38229090
InChIKey	PTKSEFOSCHHMPD-UHFFFAOYSA-N
SMILES	COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O
PubChem CID	4195

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.6
H-bond donors / acceptors	3 / 5
TPSA	93.8 Å²
Synonyms	Midodrin, 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol, DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid, Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-, 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamid, 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide, (+-)-2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)ethanimidic acid, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]ethanimidic acid, Midodrine free base, (RS)-N'-(beta-Hydroxy-2,5-dimethoxy-phenethyl)glycinamid

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Midodrine?

The CAS Registry Number of Midodrine is 42794-76-3. It is also known as Midodrin, 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol, DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid.

What is the molecular formula and molecular weight of Midodrine?

Midodrine has the molecular formula C12H18N2O4 and a molecular weight of 254.28 g/mol. Its IUPAC name is 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide.

What is Midodrine used for?

Midodrine is supplied as a characterised reference material related to Midodrine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Midodrine can I order?

We supply Midodrine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Midodrine?

Yes. Every lot of Midodrine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Midodrine be shipped internationally?

Yes. Midodrine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.