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Pharmacopeial Impurities (EP / USP / BP)Reference Standard In stock

Zopiclone EP Impurity B

Synonyms: (7RS)-6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one · 6-(5-Chloro-2-pyridinyl)-5-hydroxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine · 6-(5-Chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]pyrazine · 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one

CAS No.43200-81-3
FormulaC11H7ClN4O2
Mol. weight262.65
Catalogue No.VQ-006780
PurityReference Standard
HSN38229090

Zopiclone EP Impurity B (CAS 43200-81-3) – Zopiclone impurity standard. C11H7ClN4O2, MW 262.65. Supplied by Vaqora Chemicals with COA, exported worldwide.

Pack sizesPrice on quotation · bulk available
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25 mg
50 mg
100 mg
250 mg
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16-section GHS SDS
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About Zopiclone EP Impurity B

Zopiclone EP Impurity B (CAS 43200-81-3) is a pharmacopeial impurity of Zopiclone offered by Vaqora Chemicals. Its molecular formula is C11H7ClN4O2 and its molecular weight is 262.65 g/mol. The IUPAC name is 6-(5-chloro-2-pyridinyl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one. Alternative names: Zopiclone alcohol (USP) and C11H7ClN4O2.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Zopiclone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Zopiclone EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Zopiclone

View every impurity, metabolite and intermediate we list for Zopiclone.

Zopiclone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product nameZopiclone EP Impurity B
Catalogue No.VQ-006780
CAS Number43200-81-3
IUPAC name6-(5-chloro-2-pyridinyl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one
Molecular formulaC11H7ClN4O2
Molecular weight262.65 g/mol
Exact mass262.0258
GradeReference Standard
HSN code38229090
InChIKeyFUUXOEKDNNWZTR-UHFFFAOYSA-N
SMILESC1=CC(=NC=C1Cl)N2C(C3=NC=CN=C3C2=O)O
PubChem CID6451972
Physical properties
Physical formSolid
LogP (XLogP3)0.1
H-bond donors / acceptors1 / 5
TPSA79.2 Ų
Synonyms(7RS)-6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloro-2-pyridinyl)-5-hydroxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine, 6-(5-Chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]pyrazine, 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloro-2-pyridinyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one, Zopiclone alcohol (USP), 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo(3,4-b)pyrazin-5-one, 6-(5-chloropyridin-2-yl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-chloropyridin-2-yl)-5-hydroxy-7-oxo-5,6-dihydroprolo(3,4b)pyrazine, 6-(5-chloro-2-pyridyl)-7-hydroxy-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine-5-on, C11H7ClN4O2

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant

Signal word: Warning

Hazard statements

  • H302Harmful if swallowed
  • H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Zopiclone EP Impurity B?

The CAS Registry Number of Zopiclone EP Impurity B is 43200-81-3. It is also known as (7RS)-6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloro-2-pyridinyl)-5-hydroxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine, 6-(5-Chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]pyrazine.

What is the molecular formula and molecular weight of Zopiclone EP Impurity B?

Zopiclone EP Impurity B has the molecular formula C11H7ClN4O2 and a molecular weight of 262.65 g/mol. Its IUPAC name is 6-(5-chloro-2-pyridinyl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one.

What is Zopiclone EP Impurity B used for?

Zopiclone EP Impurity B is supplied as a characterised reference material related to Zopiclone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Zopiclone EP Impurity B can I order?

We supply Zopiclone EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Zopiclone EP Impurity B?

Yes. Every lot of Zopiclone EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Zopiclone EP Impurity B be shipped internationally?

Yes. Zopiclone EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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