Zopiclone EP Impurity B
Synonyms: (7RS)-6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one · 6-(5-Chloro-2-pyridinyl)-5-hydroxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine · 6-(5-Chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]pyrazine · 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one
Zopiclone EP Impurity B (CAS 43200-81-3) – Zopiclone impurity standard. C11H7ClN4O2, MW 262.65. Supplied by Vaqora Chemicals with COA, exported worldwide.
About Zopiclone EP Impurity B
Zopiclone EP Impurity B (CAS 43200-81-3) is a pharmacopeial impurity of Zopiclone offered by Vaqora Chemicals. Its molecular formula is C11H7ClN4O2 and its molecular weight is 262.65 g/mol. The IUPAC name is 6-(5-chloro-2-pyridinyl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one. Alternative names: Zopiclone alcohol (USP) and C11H7ClN4O2.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.
As a characterised impurity of Zopiclone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
We offer Zopiclone EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.
Typical applications
- Pharmacopeial method verification
- Impurity profiling
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Zopiclone.
Zopiclone impuritiesGrade guides
Specifications & identifiers
| Product name | Zopiclone EP Impurity B |
|---|---|
| Catalogue No. | VQ-006780 |
| CAS Number | 43200-81-3 |
| IUPAC name | 6-(5-chloro-2-pyridinyl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one |
| Molecular formula | C11H7ClN4O2 |
| Molecular weight | 262.65 g/mol |
| Exact mass | 262.0258 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | FUUXOEKDNNWZTR-UHFFFAOYSA-N |
| SMILES | C1=CC(=NC=C1Cl)N2C(C3=NC=CN=C3C2=O)O |
| PubChem CID | 6451972 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 0.1 |
| H-bond donors / acceptors | 1 / 5 |
| TPSA | 79.2 Ų |
| Synonyms | (7RS)-6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloro-2-pyridinyl)-5-hydroxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine, 6-(5-Chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]pyrazine, 6-(5-Chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloro-2-pyridinyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one, Zopiclone alcohol (USP), 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo(3,4-b)pyrazin-5-one, 6-(5-chloropyridin-2-yl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-chloropyridin-2-yl)-5-hydroxy-7-oxo-5,6-dihydroprolo(3,4b)pyrazine, 6-(5-chloro-2-pyridyl)-7-hydroxy-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine-5-on, C11H7ClN4O2 |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowedH319Causes serious eye irritation
Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Zopiclone EP Impurity B?
The CAS Registry Number of Zopiclone EP Impurity B is 43200-81-3. It is also known as (7RS)-6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one, 6-(5-Chloro-2-pyridinyl)-5-hydroxy-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine, 6-(5-Chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]pyrazine.
What is the molecular formula and molecular weight of Zopiclone EP Impurity B?
Zopiclone EP Impurity B has the molecular formula C11H7ClN4O2 and a molecular weight of 262.65 g/mol. Its IUPAC name is 6-(5-chloro-2-pyridinyl)-7-hydroxy-7H-pyrrolo[3,4-b]pyrazin-5-one.
What is Zopiclone EP Impurity B used for?
Zopiclone EP Impurity B is supplied as a characterised reference material related to Zopiclone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Zopiclone EP Impurity B can I order?
We supply Zopiclone EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Zopiclone EP Impurity B?
Yes. Every lot of Zopiclone EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Zopiclone EP Impurity B be shipped internationally?
Yes. Zopiclone EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Zopiclone EP Impurity B
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