Atorvastatin EP Impurity A (Calcium Salt)

Name: Atorvastatin EP Impurity A (Calcium Salt)
Brand: Vaqora Chemicals
SKU: VQ-006249

About Atorvastatin EP Impurity A (Calcium Salt)

Atorvastatin EP Impurity A (Calcium Salt) (CAS 433289-83-9) is a pharmacopeial impurity of Atorvastatin offered by Vaqora Chemicals. Its molecular formula is C66H70CaN4O10 and its molecular weight is 1119.4 g/mol. Its systematic (IUPAC) name is calcium bis((3R,5R)-7-[2,3-diphenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate). It is also known as Atorvastatin Related Compound A (USP) or Defluoro Atorvastatin Calcium Salt.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Atorvastatin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Atorvastatin EP Impurity A (Calcium Salt) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Atorvastatin

View every impurity, metabolite and intermediate we list for Atorvastatin.

Atorvastatin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Atorvastatin EP Impurity A (Calcium Salt)
Catalogue No.	VQ-006249
CAS Number	433289-83-9
Other CAS	433289-84-0, 1516864-05-3
IUPAC name	calcium bis((3R,5R)-7-[2,3-diphenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate)
Molecular formula	C₆₆H₇₀CaN₄O₁₀
Molecular weight	1119.4 g/mol
Exact mass	1118.4718
Grade	Reference Standard
HSN code	38229090
InChIKey	ILJBDHBNPXANQZ-MNSAWQCASA-L
SMILES	CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=CC=C2)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=CC=C2)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Ca+2]
PubChem CID	92135123

Physical properties
Physical form	Solid
H-bond donors / acceptors	6 / 10
TPSA	229 Å²
Synonyms	Atorvastatin Related Compound A (USP), Defluoro Atorvastatin Calcium Salt, Defluoro atorvastatin calcium, Atorvastatin impurity A, Desfluoroatorvastatin calcium, Atorvastatin EP Impurity ACalcium salt

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Atorvastatin EP Impurity A (Calcium Salt)?

The CAS Registry Number of Atorvastatin EP Impurity A (Calcium Salt) is 433289-83-9. It is also known as Atorvastatin Related Compound A (USP), Defluoro Atorvastatin Calcium Salt, Defluoro atorvastatin calcium.

What is the molecular formula and molecular weight of Atorvastatin EP Impurity A (Calcium Salt)?

Atorvastatin EP Impurity A (Calcium Salt) has the molecular formula C66H70CaN4O10 and a molecular weight of 1119.4 g/mol. Its IUPAC name is calcium bis((3R,5R)-7-[2,3-diphenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate).

What is Atorvastatin EP Impurity A (Calcium Salt) used for?

Atorvastatin EP Impurity A (Calcium Salt) is supplied as a characterised reference material related to Atorvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Atorvastatin EP Impurity A (Calcium Salt) can I order?

We supply Atorvastatin EP Impurity A (Calcium Salt) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Atorvastatin EP Impurity A (Calcium Salt)?

Yes. Every lot of Atorvastatin EP Impurity A (Calcium Salt) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Atorvastatin EP Impurity A (Calcium Salt) be shipped internationally?

Yes. Atorvastatin EP Impurity A (Calcium Salt) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.