Efavirenz USP Related Compound B

About Efavirenz USP Related Compound B

Efavirenz USP Related Compound B is a pharmacopeial impurity of Efavirenz carrying the CAS registry number 440124-96-9. Formula C14H11ClF3NO2, molecular weight 317.69 g/mol. Its systematic (IUPAC) name is (4S)-6-chloro-4-[(E)-2-cyclopropylethenyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Alternative names: (E)-Dihydro efavirenz and Efavirenz Related Compound B.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Efavirenz, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Efavirenz USP Related Compound B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Efavirenz

View every impurity, metabolite and intermediate we list for Efavirenz.

Efavirenz impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Efavirenz USP Related Compound B
Catalogue No.	VQ-022490
CAS Number	440124-96-9
IUPAC name	(4S)-6-chloro-4-[(E)-2-cyclopropylethenyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Molecular formula	C₁₄H₁₁ClF₃NO₂
Molecular weight	317.69 g/mol
Exact mass	317.043
Grade	Reference Standard
HSN code	38229090
InChIKey	TWWHVRKXRMMRPN-GFUIURDCSA-N
SMILES	C1CC1/C=C/[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
PubChem CID	71587736

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	1 / 5
TPSA	38.3 Å²
Synonyms	(E)-Dihydro efavirenz, Efavirenz Related Compound B, Dihydro efavirenz, (E)-, SR 695, SR-695, (S,E)-6-Chloro-4-(2-cyclopropylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one, (S,E)-6-chloro-4-(2-cyclopropylvinyl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one, Efavirenz Impurity 41, Efavirenz impurity B RS, (4S)-6-chloro-4-[(E)-2-cyclopropylvinyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Efavirenz USP Related Compound B?

The CAS Registry Number of Efavirenz USP Related Compound B is 440124-96-9. It is also known as (E)-Dihydro efavirenz, Efavirenz Related Compound B, Dihydro efavirenz, (E)-.

What is the molecular formula and molecular weight of Efavirenz USP Related Compound B?

Efavirenz USP Related Compound B has the molecular formula C14H11ClF3NO2 and a molecular weight of 317.69 g/mol. Its IUPAC name is (4S)-6-chloro-4-[(E)-2-cyclopropylethenyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one.

What is Efavirenz USP Related Compound B used for?

Efavirenz USP Related Compound B is supplied as a characterised reference material related to Efavirenz. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Efavirenz USP Related Compound B can I order?

We supply Efavirenz USP Related Compound B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Efavirenz USP Related Compound B?

Yes. Every lot of Efavirenz USP Related Compound B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Efavirenz USP Related Compound B be shipped internationally?

Yes. We export Efavirenz USP Related Compound B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.