Atorvastatin Dehydro Lactone

Name: Atorvastatin Dehydro Lactone
Brand: Vaqora Chemicals
SKU: VQ-020857

About Atorvastatin Dehydro Lactone

Atorvastatin Dehydro Lactone (CAS 442851-50-5) is an impurity of Atorvastatin offered by Vaqora Chemicals. Formula C33H31FN2O3, molecular weight 522.6 g/mol. Alternative names: 3-Dehydroxy 2,3-Dehydro Atorvastatin Lactone and Atorvastatin 2,3-Anhydro Lactone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Atorvastatin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Atorvastatin Dehydro Lactone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Atorvastatin

View every impurity, metabolite and intermediate we list for Atorvastatin.

Atorvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	Atorvastatin Dehydro Lactone
Catalogue No.	VQ-020857
CAS Number	442851-50-5
IUPAC name	5-(4-fluorophenyl)-1-[2-[(2S)-6-oxo-2,3-dihydropyran-2-yl]ethyl]-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide
Molecular formula	C₃₃H₃₁FN₂O₃
Molecular weight	522.6 g/mol
Exact mass	522.2319
Grade	Reference Standard
HSN code	38229090
InChIKey	GYIXAUAZYJKKST-MHZLTWQESA-N
SMILES	CC(C)C1=C(C(=C(N1CC[C@@H]2CC=CC(=O)O2)C3=CC=C(C=C3)F)C4=CC=CC=C4)C(=O)NC5=CC=CC=C5
PubChem CID	10186417

Physical properties
Physical form	Solid
LogP (XLogP3)	6.9
H-bond donors / acceptors	1 / 4
TPSA	60.3 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Atorvastatin Dehydro Lactone?

The CAS Registry Number of Atorvastatin Dehydro Lactone is 442851-50-5. It is also known as 3-Dehydroxy 2,3-Dehydro Atorvastatin Lactone, Atorvastatin 2,3-Anhydro Lactone.

What is the molecular formula and molecular weight of Atorvastatin Dehydro Lactone?

Atorvastatin Dehydro Lactone has the molecular formula C33H31FN2O3 and a molecular weight of 522.6 g/mol. Its IUPAC name is 5-(4-fluorophenyl)-1-[2-[(2S)-6-oxo-2,3-dihydropyran-2-yl]ethyl]-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide.

What is Atorvastatin Dehydro Lactone used for?

Atorvastatin Dehydro Lactone is supplied as a characterised reference material related to Atorvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Atorvastatin Dehydro Lactone can I order?

We supply Atorvastatin Dehydro Lactone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Atorvastatin Dehydro Lactone?

Yes. Every lot of Atorvastatin Dehydro Lactone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Atorvastatin Dehydro Lactone be shipped internationally?

Yes. Atorvastatin Dehydro Lactone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.