4-(4-Nitrophenyl)morpholin-3-one

Name: 4-(4-Nitrophenyl)morpholin-3-one
Brand: Vaqora Chemicals
SKU: VQ-033591

About 4-(4-Nitrophenyl)morpholin-3-one

Listed under CAS 446292-04-2, 4-(4-Nitrophenyl)morpholin-3-one is an impurity of Rivaroxaban available from Vaqora Chemicals. Formula C10H10N2O4, molecular weight 222.2 g/mol. Alternative names: 4-(4-Nitrophenyl)-morpholin-3-ON and 4-(4-nitrophenyl)-3-oxomorpholine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Rivaroxaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(4-Nitrophenyl)morpholin-3-one
Catalogue No.	VQ-033591
CAS Number	446292-04-2
IUPAC name	4-(4-nitrophenyl)morpholin-3-one
Molecular formula	C₁₀H₁₀N₂O₄
Molecular weight	222.2 g/mol
Exact mass	222.0641
Grade	Reference Standard
HSN code	38229090
InChIKey	OWMGEFWSGOTGAU-UHFFFAOYSA-N
SMILES	C1COCC(=O)N1C2=CC=C(C=C2)[N+](=O)[O-]
PubChem CID	11447375

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	0 / 4
TPSA	75.4 Å²
Synonyms	4-(4-Nitrophenyl)-morpholin-3-ON, 4-(4-nitrophenyl)-3-oxomorpholine, 3-Morpholinone,4-(4-nitrophenyl)-, 3-Morpholinone, 4-(4-nitrophenyl)-, 4-(3-Oxo-4-morpholinyl)nitrobenzene, CS-B0475, 4-(4-Morpholin-3-onyl)nitrobenzene, 4-(4-Morpholin-3-onyl)-nitrobenzene

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(4-Nitrophenyl)morpholin-3-one?

The CAS Registry Number of 4-(4-Nitrophenyl)morpholin-3-one is 446292-04-2. It is also known as 4-(4-Nitrophenyl)-morpholin-3-ON, 4-(4-nitrophenyl)-3-oxomorpholine, 3-Morpholinone,4-(4-nitrophenyl)-.

What is the molecular formula and molecular weight of 4-(4-Nitrophenyl)morpholin-3-one?

4-(4-Nitrophenyl)morpholin-3-one has the molecular formula C10H10N2O4 and a molecular weight of 222.2 g/mol. Its IUPAC name is 4-(4-nitrophenyl)morpholin-3-one.

What is 4-(4-Nitrophenyl)morpholin-3-one used for?

4-(4-Nitrophenyl)morpholin-3-one is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(4-Nitrophenyl)morpholin-3-one can I order?

We supply 4-(4-Nitrophenyl)morpholin-3-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(4-Nitrophenyl)morpholin-3-one?

Yes. Every lot of 4-(4-Nitrophenyl)morpholin-3-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(4-Nitrophenyl)morpholin-3-one be shipped internationally?

Yes. 4-(4-Nitrophenyl)morpholin-3-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.