Azathioprine EP Impurity A

Name: Azathioprine EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-020864

About Azathioprine EP Impurity A

Azathioprine EP Impurity A is a pharmacopeial impurity of Azathioprine carrying the CAS registry number 4531-54-8. Formula C4H6N4O2, molecular weight 142.12 g/mol. Systematically, it is named 3-methyl-5-nitroimidazol-4-amine. It is also known as Azathioprine - Impurity A or 5-amino-1-methyl-4-nitroimidazole.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Azathioprine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Azathioprine EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Azathioprine

View every impurity, metabolite and intermediate we list for Azathioprine.

Azathioprine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Azathioprine EP Impurity A
Catalogue No.	VQ-020864
CAS Number	4531-54-8
IUPAC name	3-methyl-5-nitroimidazol-4-amine
Molecular formula	C₄H₆N₄O₂
Molecular weight	142.12 g/mol
Exact mass	142.0491
Grade	Reference Standard
HSN code	38229090
InChIKey	GJVMTMXQJDQJSS-UHFFFAOYSA-N
SMILES	CN1C=NC(=C1N)[N+](=O)[O-]
PubChem CID	20625

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	1 / 4
TPSA	89.7 Å²
Synonyms	Azathioprine - Impurity A, 5-amino-1-methyl-4-nitroimidazole, 1H-Imidazol-5-amine, 1-methyl-4-nitro-, 1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI), 3-methyl-5-nitro-imidazol-4-amine, Azathioprine impurity A, 3-Methyl-5-nitro-3H-imidazol-4-ylamine, 1-methyl-4-nitroimidazole-5-ylamine, 5-amino-1-methyl-4-nitroimid-azole, (3-methyl-5-nitro-imidazol-4-yl)amine, 1-Methyl-4-nitro-1H-imidazol-5-amine #, 1-Methyl-4-nitro-1H-imidazol-5-amine (Azathioprine Impurity)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Azathioprine EP Impurity A?

The CAS Registry Number of Azathioprine EP Impurity A is 4531-54-8. It is also known as Azathioprine - Impurity A, 5-amino-1-methyl-4-nitroimidazole, 1H-Imidazol-5-amine, 1-methyl-4-nitro-.

What is the molecular formula and molecular weight of Azathioprine EP Impurity A?

Azathioprine EP Impurity A has the molecular formula C4H6N4O2 and a molecular weight of 142.12 g/mol. Its IUPAC name is 3-methyl-5-nitroimidazol-4-amine.

What is Azathioprine EP Impurity A used for?

Azathioprine EP Impurity A is supplied as a characterised reference material related to Azathioprine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Azathioprine EP Impurity A can I order?

We supply Azathioprine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Azathioprine EP Impurity A?

Yes. Every lot of Azathioprine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Azathioprine EP Impurity A be shipped internationally?

Yes. Azathioprine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.