2,5-Dimethyl Celecoxib

Name: 2,5-Dimethyl Celecoxib
Brand: Vaqora Chemicals
SKU: VQ-034810

About 2,5-Dimethyl Celecoxib

Listed under CAS 457639-26-8, 2,5-Dimethyl Celecoxib is an impurity of Celecoxib available from Vaqora Chemicals. Its molecular formula is C18H16F3N3O2S and its molecular weight is 395.4 g/mol. Its systematic (IUPAC) name is 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide. Common synonyms include Celecoxib 2,5-Dimethyl and Dimethyl Celecoxib.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Celecoxib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Celecoxib

View every impurity, metabolite and intermediate we list for Celecoxib.

Celecoxib impurities

Specifications & identifiers

Chemical identifiers
Product name	2,5-Dimethyl Celecoxib
Catalogue No.	VQ-034810
CAS Number	457639-26-8
IUPAC name	4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Molecular formula	C₁₈H₁₆F₃N₃O₂S
Molecular weight	395.4 g/mol
Exact mass	395.0915
Grade	Reference Standard
HSN code	38229090
InChIKey	NTFOSUUWGCDXEF-UHFFFAOYSA-N
SMILES	CC1=CC(=C(C=C1)C)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
PubChem CID	11545682

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 7
TPSA	86.4 Å²
Synonyms	Celecoxib 2,5-Dimethyl, 4-(5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl]benzenesulfonamide, Dimethyl Celecoxib, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide, 2,5-dimethyl Celecoxib, DMC, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide, Benzenesulfonamide, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,5-Dimethyl Celecoxib?

The CAS Registry Number of 2,5-Dimethyl Celecoxib is 457639-26-8. It is also known as Celecoxib 2,5-Dimethyl, 4-(5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl]benzenesulfonamide.

What is the molecular formula and molecular weight of 2,5-Dimethyl Celecoxib?

2,5-Dimethyl Celecoxib has the molecular formula C18H16F3N3O2S and a molecular weight of 395.4 g/mol. Its IUPAC name is 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide.

What is 2,5-Dimethyl Celecoxib used for?

2,5-Dimethyl Celecoxib is supplied as a characterised reference material related to Celecoxib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,5-Dimethyl Celecoxib can I order?

We supply 2,5-Dimethyl Celecoxib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,5-Dimethyl Celecoxib?

Yes. Every lot of 2,5-Dimethyl Celecoxib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,5-Dimethyl Celecoxib be shipped internationally?

Yes. 2,5-Dimethyl Celecoxib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.