Dacarbazine EP Impurity A

About Dacarbazine EP Impurity A

Dacarbazine EP Impurity A is a pharmacopeial impurity of Dacarbazine carrying the CAS registry number 4656-86-4. With the molecular formula C4H3N5O, it has a molar mass of 137.1 g/mol. Systematically, it is named 3,5-dihydroimidazo[4,5-d]triazin-4-one. It is also known as Temozolomide EP Impurity E or Dacarbazine - Impurity A.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Dacarbazine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dacarbazine EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dacarbazine

View every impurity, metabolite and intermediate we list for Dacarbazine.

Dacarbazine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dacarbazine EP Impurity A
Catalogue No.	VQ-022298
CAS Number	4656-86-4
IUPAC name	3,5-dihydroimidazo[4,5-d]triazin-4-one
Molecular formula	C₄H₃N₅O
Molecular weight	137.1 g/mol
Exact mass	137.0338
Grade	Reference Standard
HSN code	38229090
InChIKey	BTERLCQQBYXVIN-UHFFFAOYSA-N
SMILES	C1=NC2=C(N1)C(=O)NN=N2
PubChem CID	135421876

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	2 / 4
TPSA	82.5 Å²
Synonyms	Temozolomide EP Impurity E, Dacarbazine - Impurity A, Temozolomide 2-Azahypoxanthine Impurity, Temozolomide - Impurity E, 2-Azahypoxanthine, 3,7-Dihydro-4H-imidazo[4,5-d]-1,2,3-triazin-4-one, 3,5-dihydroimidazo(4,5-d)triazin-4-one, 1,5-dihydro-4H-imidazo[4,5-d]-1,2,3-triazin-4-one, Dacarbazine Impurity A, 3H-Imidazo[4,5-d][1,2,3]triazin-4(7H)-one, 3H,4H,7H-imidazo[4,5-d][1,2,3]triazin-4-one, 3,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H341Suspected of causing genetic defects
H351Suspected of causing cancer

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dacarbazine EP Impurity A?

The CAS Registry Number of Dacarbazine EP Impurity A is 4656-86-4. It is also known as Temozolomide EP Impurity E, Dacarbazine - Impurity A, Temozolomide 2-Azahypoxanthine Impurity.

What is the molecular formula and molecular weight of Dacarbazine EP Impurity A?

Dacarbazine EP Impurity A has the molecular formula C4H3N5O and a molecular weight of 137.1 g/mol. Its IUPAC name is 3,5-dihydroimidazo[4,5-d]triazin-4-one.

What is Dacarbazine EP Impurity A used for?

Dacarbazine EP Impurity A is supplied as a characterised reference material related to Dacarbazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dacarbazine EP Impurity A can I order?

We supply Dacarbazine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dacarbazine EP Impurity A?

Yes. Every lot of Dacarbazine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dacarbazine EP Impurity A be shipped internationally?

Yes. Dacarbazine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.