5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indano… 4803-74-1

Name: 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
Brand: Vaqora Chemicals
SKU: VQ-022431

About 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone (CAS 4803-74-1) is an impurity of Donepezil offered by Vaqora Chemicals. The compound has the formula C17H15NO3, corresponding to a molecular weight of 281.3 g/mol. Its systematic (IUPAC) name is (2E)-5,6-dimethoxy-2-(pyridin-4-ylmethylidene)-3H-inden-1-one. Common synonyms include Donepezil pyridine dehydro Imp and Donepezil HCL Intermediates 1.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Donepezil, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Specifications & identifiers

Chemical identifiers
Product name	5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
Catalogue No.	VQ-022431
CAS Number	4803-74-1
IUPAC name	(2E)-5,6-dimethoxy-2-(pyridin-4-ylmethylidene)-3H-inden-1-one
Molecular formula	C₁₇H₁₅NO₃
Molecular weight	281.3 g/mol
Exact mass	281.1052
Grade	Reference Standard
HSN code	38229090
InChIKey	SUVQWDLUAIFZKM-NTUHNPAUSA-N
SMILES	COC1=C(C=C2C(=C1)C/C(=C\C3=CC=NC=C3)/C2=O)OC
PubChem CID	11572727

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	0 / 4
TPSA	48.4 Å²
Synonyms	2,3-dihydro-5,6-dimethoxy-2-(4-pyridinylmethylene)-1h-inden-1-one, 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one, 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one, 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-(4-pyridinylmethylene)-, 5,6-Dimethoxyl-2-(piperidin-4-y)methylene-indan-1-one, (E)-5,6-dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one, (5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one), Donepezil pyridine dehydro Imp, Donepezil HCL Intermediates 1, Doneprzil Pyridine Dehydro Imp

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone?

The CAS Registry Number of 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is 4803-74-1. It is also known as 2,3-dihydro-5,6-dimethoxy-2-(4-pyridinylmethylene)-1h-inden-1-one, 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one, 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one.

What is the molecular formula and molecular weight of 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone?

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone has the molecular formula C17H15NO3 and a molecular weight of 281.3 g/mol. Its IUPAC name is (2E)-5,6-dimethoxy-2-(pyridin-4-ylmethylidene)-3H-inden-1-one.

What is 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone used for?

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone can I order?

We supply 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone?

Yes. Every lot of 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone be shipped internationally?

Yes. We export 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.