(-)-Norephedrine

Name: (-)-Norephedrine
Brand: Vaqora Chemicals
SKU: VQ-019836

About (-)-Norephedrine

Listed under CAS 492-41-1, (-)-Norephedrine is a metabolite or degradation product of Ephedrine available from Vaqora Chemicals. Its molecular formula is C9H13NO and its molecular weight is 151.21 g/mol. Its systematic (IUPAC) name is (1R,2S)-2-amino-1-phenylpropan-1-ol. Alternative names: L-Norephedrine Base and phenylpropanolamine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Ephedrine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (-)-Norephedrine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ephedrine

View every impurity, metabolite and intermediate we list for Ephedrine.

Ephedrine impurities

Specifications & identifiers

Chemical identifiers
Product name	(-)-Norephedrine
Catalogue No.	VQ-019836
CAS Number	492-41-1
IUPAC name	(1R,2S)-2-amino-1-phenylpropan-1-ol
Molecular formula	C₉H₁₃NO
Molecular weight	151.21 g/mol
Exact mass	151.0997
Grade	Reference Standard
HSN code	38229090
InChIKey	DLNKOYKMWOXYQA-CBAPKCEASA-N
SMILES	C[C@@H]([C@@H](C1=CC=CC=C1)O)N
PubChem CID	10297

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	2 / 2
TPSA	46.3 Å²
Synonyms	L-Norephedrine Base, phenylpropanolamine, Propadrine, Phenylfenesin, Rinexin, erythro-2-Amino-1-phenyl-1-propanol, Benzenemethanol, alpha-(1-aminoethyl)-, (R,S)-(+-)-, Phenylpropanolamine 1534, 2-amino-1-phenylpropan-1-ol, l-Norephedrine, (1R,2S)-Norephedrine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (-)-Norephedrine?

The CAS Registry Number of (-)-Norephedrine is 492-41-1. It is also known as L-Norephedrine Base, phenylpropanolamine, Propadrine.

What is the molecular formula and molecular weight of (-)-Norephedrine?

(-)-Norephedrine has the molecular formula C9H13NO and a molecular weight of 151.21 g/mol. Its IUPAC name is (1R,2S)-2-amino-1-phenylpropan-1-ol.

What is (-)-Norephedrine used for?

(-)-Norephedrine is supplied as a characterised reference material related to Ephedrine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (-)-Norephedrine can I order?

We supply (-)-Norephedrine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (-)-Norephedrine?

Yes. Every lot of (-)-Norephedrine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (-)-Norephedrine be shipped internationally?

Yes. (-)-Norephedrine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.