Dimenhydrinate EP Impurity E

About Dimenhydrinate EP Impurity E

Dimenhydrinate EP Impurity E is a pharmacopeial impurity of Dimenhydrinate carrying the CAS registry number 4921-49-7. Formula C8H9ClN4O2, molecular weight 228.63 g/mol. Systematically, it is named 8-chloro-1,3,7-trimethylpurine-2,6-dione. It is also known as 8-Chloro Caffeine or Dimenhydrinate - Impurity E.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Dimenhydrinate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dimenhydrinate

View every impurity, metabolite and intermediate we list for Dimenhydrinate.

Dimenhydrinate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dimenhydrinate EP Impurity E
Catalogue No.	VQ-022391
CAS Number	4921-49-7
IUPAC name	8-chloro-1,3,7-trimethylpurine-2,6-dione
Molecular formula	C₈H₉ClN₄O₂
Molecular weight	228.63 g/mol
Exact mass	228.0414
Grade	Reference Standard
HSN code	38229090
InChIKey	HGKPGBJNNATDRR-UHFFFAOYSA-N
SMILES	CN1C2=C(N=C1Cl)N(C(=O)N(C2=O)C)C
PubChem CID	21031

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	0 / 3
TPSA	58.4 Å²
Synonyms	8-Chloro Caffeine, Dimenhydrinate - Impurity E, 8-Chlorocaffeine, 1H-Purine-2,6-dione, 8-chloro-3,7-dihydro-1,3,7-trimethyl-, 8-Chloro-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, 8-chloro-1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, 8-Chloro-1,3,7-trimethyl-1H-purine-2,6(3H,7H)-dione, 8-chloro-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione, 8-Chloro-1,3,7-trimethylxanthine, 8-Chloro-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione (8-Chlorocaffeine), Caffeine, 8-chloro, 8-chloro-1,3,7-trimethyl-purine-2,6-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dimenhydrinate EP Impurity E?

The CAS Registry Number of Dimenhydrinate EP Impurity E is 4921-49-7. It is also known as 8-Chloro Caffeine, Dimenhydrinate - Impurity E, 8-Chlorocaffeine.

What is the molecular formula and molecular weight of Dimenhydrinate EP Impurity E?

Dimenhydrinate EP Impurity E has the molecular formula C8H9ClN4O2 and a molecular weight of 228.63 g/mol. Its IUPAC name is 8-chloro-1,3,7-trimethylpurine-2,6-dione.

What is Dimenhydrinate EP Impurity E used for?

Dimenhydrinate EP Impurity E is supplied as a characterised reference material related to Dimenhydrinate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dimenhydrinate EP Impurity E can I order?

We supply Dimenhydrinate EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dimenhydrinate EP Impurity E?

Yes. Every lot of Dimenhydrinate EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dimenhydrinate EP Impurity E be shipped internationally?

Yes. Dimenhydrinate EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.