Apoatropine

About Apoatropine

Apoatropine is an impurity of Atropine carrying the CAS registry number 500-55-0. The compound has the formula C17H21NO2, corresponding to a molecular weight of 271.35 g/mol. Its systematic (IUPAC) name is (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-phenylprop-2-enoate. Common synonyms include Atropamine and Apohyoscyamine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Atropine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Apoatropine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Atropine

View every impurity, metabolite and intermediate we list for Atropine.

Atropine impurities

Specifications & identifiers

Chemical identifiers
Product name	Apoatropine
Catalogue No.	VQ-024435
CAS Number	500-55-0
IUPAC name	(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-phenylprop-2-enoate
Molecular formula	C₁₇H₂₁NO₂
Molecular weight	271.35 g/mol
Exact mass	271.1572
Grade	Reference Standard
HSN code	38229090
InChIKey	WPUIZWXOSDVQJU-UHFFFAOYSA-N
SMILES	CN1C2CCC1CC(C2)OC(=O)C(=C)C3=CC=CC=C3
PubChem CID	64695

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	0 / 3
TPSA	29.5 Å²
Synonyms	Atropamine, Apohyoscyamine, Atropyltropeine, Apohyoscyamin, (8-methyl-8-azabicyclo(3.2.1)octan-3-yl) 2-phenylprop-2-enoate, Benzeneacetic acid, alpha-methylene-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-, Apoatropin, Atropamin, Benzeneacetic acid, alpha-methylene-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, Atropine - H2O, Benzeneacetic acid, .alpha.-methylene-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-, 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl atropate #

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Apoatropine?

The CAS Registry Number of Apoatropine is 500-55-0. It is also known as Atropamine, Apohyoscyamine, Atropyltropeine.

What is the molecular formula and molecular weight of Apoatropine?

Apoatropine has the molecular formula C17H21NO2 and a molecular weight of 271.35 g/mol. Its IUPAC name is (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-phenylprop-2-enoate.

What is Apoatropine used for?

Apoatropine is supplied as a characterised reference material related to Atropine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Apoatropine can I order?

We supply Apoatropine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Apoatropine?

Yes. Every lot of Apoatropine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Apoatropine be shipped internationally?

Yes. We export Apoatropine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.