Rosuvastatin EP Impurity D

Name: Rosuvastatin EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-006678

About Rosuvastatin EP Impurity D

Listed under CAS 503610-43-3, Rosuvastatin EP Impurity D is a pharmacopeial impurity of Rosuvastatin available from Vaqora Chemicals. Formula C22H26FN3O5S, molecular weight 463.5 g/mol. Alternative names: Rosuvastatin lactone and Rosuvastatin-5S-lactone.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Rosuvastatin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rosuvastatin EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Rosuvastatin EP Impurity D
Catalogue No.	VQ-006678
CAS Number	503610-43-3
IUPAC name	N-[4-(4-fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
Molecular formula	C₂₂H₂₆FN₃O₅S
Molecular weight	463.5 g/mol
Exact mass	463.1577
Grade	Reference Standard
HSN code	38229090
InChIKey	SOEGVMSNJOCVHT-VEUZHWNKSA-N
SMILES	CC(C)C1=NC(=NC(=C1/C=C/[C@@H]2C[C@H](CC(=O)O2)O)C3=CC=C(C=C3)F)N(C)S(=O)(=O)C
PubChem CID	29918986

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 9
TPSA	118 Å²
Synonyms	Rosuvastatin lactone, Rosuvastatin-5S-lactone, ent-Rosuvastatin Lactone, Rosuvastatin 5 S-lactone, Rosuvastatin-5-S-lactone

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rosuvastatin EP Impurity D?

The CAS Registry Number of Rosuvastatin EP Impurity D is 503610-43-3. It is also known as Rosuvastatin lactone, Rosuvastatin-5S-lactone, ent-Rosuvastatin Lactone.

What is the molecular formula and molecular weight of Rosuvastatin EP Impurity D?

Rosuvastatin EP Impurity D has the molecular formula C22H26FN3O5S and a molecular weight of 463.5 g/mol. Its IUPAC name is N-[4-(4-fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide.

What is Rosuvastatin EP Impurity D used for?

Rosuvastatin EP Impurity D is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rosuvastatin EP Impurity D can I order?

We supply Rosuvastatin EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rosuvastatin EP Impurity D?

Yes. Every lot of Rosuvastatin EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rosuvastatin EP Impurity D be shipped internationally?

Yes. Rosuvastatin EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.