Granisetron EP Impurity D

Name: Granisetron EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-022771

About Granisetron EP Impurity D

Granisetron EP Impurity D (CAS 50890-83-0) is a pharmacopeial impurity of Granisetron offered by Vaqora Chemicals. Formula C9H8N2O2, molecular weight 176.17 g/mol. Systematically, it is named 1-methylindazole-3-carboxylic acid. Common synonyms include Granisetron Hydrochloride - Impurity D and 1-methyl-1H-indazole-3-carboxylic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Granisetron to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Granisetron EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Granisetron

View every impurity, metabolite and intermediate we list for Granisetron.

Granisetron impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Granisetron EP Impurity D
Catalogue No.	VQ-022771
CAS Number	50890-83-0
IUPAC name	1-methylindazole-3-carboxylic acid
Molecular formula	C₉H₈N₂O₂
Molecular weight	176.17 g/mol
Exact mass	176.0586
Grade	Reference Standard
HSN code	38229090
InChIKey	OVVDFORZEGKEJM-UHFFFAOYSA-N
SMILES	CN1C2=CC=CC=C2C(=N1)C(=O)O
PubChem CID	689105

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 3
TPSA	55.1 Å²
Synonyms	Granisetron Hydrochloride - Impurity D, 1-methyl-1H-indazole-3-carboxylic acid, 1H-Indazole-3-carboxylic acid, 1-methyl-, 1-Methylindazole-3-carboxylic Acid (Granisetron Impurity D), Granisetron Impurity 15, N-Methyl-indazole-3-carboxylic acid, 1-Methyl-1H-indazole-3-carboxylicacid, 1-Methyl-indazole-3-carboxylic acid, Granisetron impurity D, Granisetron intermediate, n-methylindazole-3-carboxylic acid, 1-methyl-3-indazolylcarboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Granisetron EP Impurity D?

The CAS Registry Number of Granisetron EP Impurity D is 50890-83-0. It is also known as Granisetron Hydrochloride - Impurity D, 1-methyl-1H-indazole-3-carboxylic acid, 1H-Indazole-3-carboxylic acid, 1-methyl-.

What is the molecular formula and molecular weight of Granisetron EP Impurity D?

Granisetron EP Impurity D has the molecular formula C9H8N2O2 and a molecular weight of 176.17 g/mol. Its IUPAC name is 1-methylindazole-3-carboxylic acid.

What is Granisetron EP Impurity D used for?

Granisetron EP Impurity D is supplied as a characterised reference material related to Granisetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Granisetron EP Impurity D can I order?

We supply Granisetron EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Granisetron EP Impurity D?

Yes. Every lot of Granisetron EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Granisetron EP Impurity D be shipped internationally?

Yes. Granisetron EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.