(1`R,2`S)-Cis-Nicotine-1`-N-oxide
Synonyms: (1'R,2'S)-Nicotine 1'-Oxide · Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)- · (1R,2S)-Anti-nicotine N'-oxide · Nicotine N'-oxide, (1'R,2'S)-
(1`R,2`S)-Cis-Nicotine-1`-N-oxide (CAS 51020-67-8) – Nicotine impurity standard. C10H14N2O, MW 178.23. COA included. Worldwide shipping from Vaqora Chemicals.
About (1`R,2`S)-Cis-Nicotine-1`-N-oxide
Listed under CAS 51020-67-8, (1`R,2`S)-Cis-Nicotine-1`-N-oxide is a metabolite or degradation product of Nicotine available from Vaqora Chemicals. With the molecular formula C10H14N2O, it has a molar mass of 178.23 g/mol. The IUPAC name is 3-[(1R,2S)-1-methyl-1-oxidopyrrolidin-1-ium-2-yl]pyridine. Common synonyms include (1'R,2'S)-Nicotine 1'-Oxide and (1R,2S)-Anti-nicotine N'-oxide.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.
It is used in metabolite identification, stability-indicating method development and impurity profiling of Nicotine, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Industries
View every impurity, metabolite and intermediate we list for Nicotine.
Nicotine impuritiesSpecifications & identifiers
| Product name | (1`R,2`S)-Cis-Nicotine-1`-N-oxide |
|---|---|
| Catalogue No. | VQ-032141 |
| CAS Number | 51020-67-8 |
| IUPAC name | 3-[(1R,2S)-1-methyl-1-oxidopyrrolidin-1-ium-2-yl]pyridine |
| Molecular formula | C10H14N2O |
| Molecular weight | 178.23 g/mol |
| Exact mass | 178.1106 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | RWFBQHICRCUQJJ-CMPLNLGQSA-N |
| SMILES | C[N@+]1(CCC[C@H]1C2=CN=CC=C2)[O-] |
| PubChem CID | 10888489 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 0.7 |
| H-bond donors / acceptors | 0 / 2 |
| TPSA | 31 Ų |
| Synonyms | (1'R,2'S)-Nicotine 1'-Oxide, Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)-, (1R,2S)-Anti-nicotine N'-oxide, Nicotine N'-oxide, (1'R,2'S)-, 1'(R),2'(S)-cis-Nicotine-N'-oxide, 1'(R),2'(S)-cis-Nicotine-N'-oxide, (-)-, 3-(1-Methyl-2-pyrrolidinyl)-pyridine, N-oxide, (1R-trans)-, cis-NOX, cis-(S)-nicotine N(1')-oxide, (1'R,2'S)-nicotine N'-oxide |
Documents
Frequently asked questions
What is the CAS number of (1`R,2`S)-Cis-Nicotine-1`-N-oxide?
The CAS Registry Number of (1`R,2`S)-Cis-Nicotine-1`-N-oxide is 51020-67-8. It is also known as (1'R,2'S)-Nicotine 1'-Oxide, Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)-, (1R,2S)-Anti-nicotine N'-oxide.
What is the molecular formula and molecular weight of (1`R,2`S)-Cis-Nicotine-1`-N-oxide?
(1`R,2`S)-Cis-Nicotine-1`-N-oxide has the molecular formula C10H14N2O and a molecular weight of 178.23 g/mol. Its IUPAC name is 3-[(1R,2S)-1-methyl-1-oxidopyrrolidin-1-ium-2-yl]pyridine.
What is (1`R,2`S)-Cis-Nicotine-1`-N-oxide used for?
(1`R,2`S)-Cis-Nicotine-1`-N-oxide is supplied as a characterised reference material related to Nicotine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of (1`R,2`S)-Cis-Nicotine-1`-N-oxide can I order?
We supply (1`R,2`S)-Cis-Nicotine-1`-N-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with (1`R,2`S)-Cis-Nicotine-1`-N-oxide?
Yes. Every lot of (1`R,2`S)-Cis-Nicotine-1`-N-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can (1`R,2`S)-Cis-Nicotine-1`-N-oxide be shipped internationally?
Yes. We export (1`R,2`S)-Cis-Nicotine-1`-N-oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about (1`R,2`S)-Cis-Nicotine-1`-N-oxide
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