(E)-Ethyl 4-Bromo-3-methyl-2-butenoate

Name: (E)-Ethyl 4-Bromo-3-methyl-2-butenoate
Brand: Vaqora Chemicals
SKU: VQ-031295

About (E)-Ethyl 4-Bromo-3-methyl-2-butenoate

Vaqora Chemicals supplies (E)-Ethyl 4-Bromo-3-methyl-2-butenoate, an impurity of Isotretinoin registered under CAS number 51318-62-8. Its molecular formula is C7H11BrO2 and its molecular weight is 207.06 g/mol. The IUPAC name is ethyl (E)-4-bromo-3-methylbut-2-enoate. Common synonyms include ethyl-4-bromo-3-methylbut-2-enoate and ethyl 4-bromo-3-methyl-2-butenoate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Isotretinoin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer (E)-Ethyl 4-Bromo-3-methyl-2-butenoate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-Ethyl 4-Bromo-3-methyl-2-butenoate
Catalogue No.	VQ-031295
CAS Number	51318-62-8
IUPAC name	ethyl (E)-4-bromo-3-methylbut-2-enoate
Molecular formula	C₇H₁₁BrO₂
Molecular weight	207.06 g/mol
Exact mass	205.9942
Grade	Reference Standard
HSN code	38229090
InChIKey	JIPWHZOYUGYXFA-GQCTYLIASA-N
SMILES	CCOC(=O)/C=C(\C)/CBr
PubChem CID	11095793

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	ethyl-4-bromo-3-methylbut-2-enoate, ethyl 4-bromo-3-methyl-2-butenoate, ethyl 4-bromo-3-methylbut-2-enoate, ethyl 4-bromo-3-methylcrotonate, trans-5-Bromo-1-ethoxy-4-methylpent-3-en-2-one, 2-Butenoic acid, 4-bromo-3-methyl-, ethyl ester, (E)-, ethyl-4-bromo-3-methyl-2-butenoate, Ethyl-4-bromo-3-methyl-but-2-enoate, 4-bromo-3-methylcrotonoic acid ethyl ester, ethyl (E)-4-bromo-3-methyl-but-2-enoate, 2-Butenoic acid, 4-bromo-3-methyl-, ethyl ester, (Z)-

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H332Harmful if inhaled

Precautionary statements: P260, P261, P264, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P321, P330, P362 + P364, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-Ethyl 4-Bromo-3-methyl-2-butenoate?

The CAS Registry Number of (E)-Ethyl 4-Bromo-3-methyl-2-butenoate is 51318-62-8. It is also known as ethyl-4-bromo-3-methylbut-2-enoate, ethyl 4-bromo-3-methyl-2-butenoate, ethyl 4-bromo-3-methylbut-2-enoate.

What is the molecular formula and molecular weight of (E)-Ethyl 4-Bromo-3-methyl-2-butenoate?

(E)-Ethyl 4-Bromo-3-methyl-2-butenoate has the molecular formula C7H11BrO2 and a molecular weight of 207.06 g/mol. Its IUPAC name is ethyl (E)-4-bromo-3-methylbut-2-enoate.

What is (E)-Ethyl 4-Bromo-3-methyl-2-butenoate used for?

(E)-Ethyl 4-Bromo-3-methyl-2-butenoate is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-Ethyl 4-Bromo-3-methyl-2-butenoate can I order?

We supply (E)-Ethyl 4-Bromo-3-methyl-2-butenoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-Ethyl 4-Bromo-3-methyl-2-butenoate?

Yes. Every lot of (E)-Ethyl 4-Bromo-3-methyl-2-butenoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-Ethyl 4-Bromo-3-methyl-2-butenoate be shipped internationally?

Yes. (E)-Ethyl 4-Bromo-3-methyl-2-butenoate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.