4-Fluoro-3-hydroxybenzoic acid

Name: 4-Fluoro-3-hydroxybenzoic acid
Brand: Vaqora Chemicals
SKU: VQ-051634

About 4-Fluoro-3-hydroxybenzoic acid

4-Fluoro-3-hydroxybenzoic acid (CAS 51446-31-2) is a metabolite or degradation product of Acoramidis offered by Vaqora Chemicals. Its molecular formula is C7H5FO3 and its molecular weight is 156.11 g/mol. Alternative names: Benzoic acid, 4-fluoro-3-hydroxy- and 3-hydroxy-4-fluorobenzoic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Acoramidis, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Fluoro-3-hydroxybenzoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Acoramidis

View every impurity, metabolite and intermediate we list for Acoramidis.

Acoramidis impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Fluoro-3-hydroxybenzoic acid
Catalogue No.	VQ-051634
CAS Number	51446-31-2
IUPAC name	4-fluoro-3-hydroxybenzoic acid
Molecular formula	C₇H₅FO₃
Molecular weight	156.11 g/mol
Exact mass	156.0223
Grade	Reference Standard
HSN code	38229090
InChIKey	QATKOZUHTGAWMG-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1C(=O)O)O)F
PubChem CID	593635

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	2 / 4
TPSA	57.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Fluoro-3-hydroxybenzoic acid?

The CAS Registry Number of 4-Fluoro-3-hydroxybenzoic acid is 51446-31-2. It is also known as Benzoic acid, 4-fluoro-3-hydroxy-, 3-hydroxy-4-fluorobenzoic acid, 3-hydroxy-4-fluoro-benzoic acid.

What is the molecular formula and molecular weight of 4-Fluoro-3-hydroxybenzoic acid?

4-Fluoro-3-hydroxybenzoic acid has the molecular formula C7H5FO3 and a molecular weight of 156.11 g/mol. Its IUPAC name is 4-fluoro-3-hydroxybenzoic acid.

What is 4-Fluoro-3-hydroxybenzoic acid used for?

4-Fluoro-3-hydroxybenzoic acid is supplied as a characterised reference material related to Acoramidis. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Fluoro-3-hydroxybenzoic acid can I order?

We supply 4-Fluoro-3-hydroxybenzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Fluoro-3-hydroxybenzoic acid?

Yes. Every lot of 4-Fluoro-3-hydroxybenzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Fluoro-3-hydroxybenzoic acid be shipped internationally?

Yes. 4-Fluoro-3-hydroxybenzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.