N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybut… 52322-22-2

Name: N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide)
Brand: Vaqora Chemicals
SKU: VQ-037121

About N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide)

Vaqora Chemicals supplies N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide), a nitrosamine impurity of Ethambutol registered under CAS number 52322-22-2. Its molecular formula is C10H22N4O4 and its molecular weight is 262.31 g/mol. Its systematic (IUPAC) name is N-[(2R)-1-hydroxybutan-2-yl]-N-[2-[[(2R)-1-hydroxybutan-2-yl]-nitrosoamino]ethyl]nitrous amide. It is also known as Dinitrosoethambutol, (R,R)- or (R,R)-dinitrosoethambutol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Ethambutol

View every impurity, metabolite and intermediate we list for Ethambutol.

Ethambutol impurities

Specifications & identifiers

Chemical identifiers
Product name	N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide)
Catalogue No.	VQ-037121
CAS Number	52322-22-2
IUPAC name	N-[(2R)-1-hydroxybutan-2-yl]-N-[2-[[(2R)-1-hydroxybutan-2-yl]-nitrosoamino]ethyl]nitrous amide
Molecular formula	C₁₀H₂₂N₄O₄
Molecular weight	262.31 g/mol
Exact mass	262.1641
Grade	Reference Standard
HSN code	38229090
InChIKey	GEIAKCPGVIYGOY-NXEZZACHSA-N
SMILES	CC[C@H](CO)N(CCN([C@H](CC)CO)N=O)N=O
PubChem CID	121489302

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 8
TPSA	106 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide)?

The CAS Registry Number of N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) is 52322-22-2. It is also known as Dinitrosoethambutol, (R,R)-, d-N,N'-Bisnitroso-N,N'-bis(1-hydroxymethylpropyl)ethylenediamine, (R,R)-dinitrosoethambutol.

What is the molecular formula and molecular weight of N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide)?

N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) has the molecular formula C10H22N4O4 and a molecular weight of 262.31 g/mol. Its IUPAC name is N-[(2R)-1-hydroxybutan-2-yl]-N-[2-[[(2R)-1-hydroxybutan-2-yl]-nitrosoamino]ethyl]nitrous amide.

What is N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) used for?

N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) is supplied as a characterised reference material related to Ethambutol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) can I order?

We supply N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide)?

Yes. Every lot of N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) be shipped internationally?

Yes. We export N,N'-(Ethane-1,2-diyl)bis(N-((R)-1-hydroxybutan-2-yl)nitrous amide) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.