Chlorthalidone EP Impurity B

Name: Chlorthalidone EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-021138

About Chlorthalidone EP Impurity B

Chlorthalidone EP Impurity B (CAS 5270-74-6) is a pharmacopeial impurity of Chlorthalidone offered by Vaqora Chemicals. Formula C14H10ClNO5S, molecular weight 339.8 g/mol. Its systematic (IUPAC) name is 2-(4-chloro-3-sulfamoylbenzoyl)benzoic acid. Common synonyms include Chlortalidone EP Impurity B and Chlortalidone - Impurity B.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Chlorthalidone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Chlorthalidone EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Chlorthalidone

View every impurity, metabolite and intermediate we list for Chlorthalidone.

Chlorthalidone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Chlorthalidone EP Impurity B
Catalogue No.	VQ-021138
CAS Number	5270-74-6
IUPAC name	2-(4-chloro-3-sulfamoylbenzoyl)benzoic acid
Molecular formula	C₁₄H₁₀ClNO₅S
Molecular weight	339.8 g/mol
Exact mass	338.9968
Grade	Reference Standard
HSN code	38229090
InChIKey	UKRADWWBRBBJLZ-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N)C(=O)O
PubChem CID	78924

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 6
TPSA	123 Å²
Synonyms	Chlortalidone EP Impurity B, Chlorthalidone EP Impurity B/ chlorthalidone USP rc a, Chlortalidone - Impurity B, Chlorthalidone Impurity B, 2-(4-Chloro-3-sulphamoylbenzoyl)benzoic acid, 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]benzoic acid, 4'-Chloro-3'-sulfamoyl-2-benzophenone carboxylic acid, Benzoic acid, 2-(3-(aminosulfonyl)-4-chlorobenzoyl)-, Benzoic acid, 2-[3-(aminosulfonyl)-4-chlorobenzoyl]-, Chlorthalidone impurity, Chlorthalidone Impurity A, 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Chlorthalidone EP Impurity B?

The CAS Registry Number of Chlorthalidone EP Impurity B is 5270-74-6. It is also known as Chlortalidone EP Impurity B, Chlorthalidone EP Impurity B/ chlorthalidone USP rc a, Chlortalidone - Impurity B.

What is the molecular formula and molecular weight of Chlorthalidone EP Impurity B?

Chlorthalidone EP Impurity B has the molecular formula C14H10ClNO5S and a molecular weight of 339.8 g/mol. Its IUPAC name is 2-(4-chloro-3-sulfamoylbenzoyl)benzoic acid.

What is Chlorthalidone EP Impurity B used for?

Chlorthalidone EP Impurity B is supplied as a characterised reference material related to Chlorthalidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlorthalidone EP Impurity B can I order?

We supply Chlorthalidone EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlorthalidone EP Impurity B?

Yes. Every lot of Chlorthalidone EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlorthalidone EP Impurity B be shipped internationally?

Yes. Chlorthalidone EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.