2-Nitro-p-phenylenediamine

Name: 2-Nitro-p-phenylenediamine
Brand: Vaqora Chemicals
SKU: VQ-012966

About 2-Nitro-p-phenylenediamine

2-Nitro-p-phenylenediamine (CAS 5307-14-2) is a process intermediate or related compound of Retigabine offered by Vaqora Chemicals, specified at 70% purity. The compound has the formula C6H7N3O2, corresponding to a molecular weight of 153.14 g/mol. The IUPAC name is 2-nitrobenzene-1,4-diamine. Alternative names: 2-Nitro-1,4-benzenediamine and 1,4-Diamino-2-nitrobenzene.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Retigabine, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Nitro-p-phenylenediamine is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Retigabine

View every impurity, metabolite and intermediate we list for Retigabine.

Retigabine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Nitro-p-phenylenediamine
Catalogue No.	VQ-012966
CAS Number	5307-14-2
IUPAC name	2-nitrobenzene-1,4-diamine
Molecular formula	C₆H₇N₃O₂
Molecular weight	153.14 g/mol
Exact mass	153.0538
Grade	Reference Standard
Purity / assay	70%
HSN code	2933
InChIKey	HVHNMNGARPCGGD-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1N)[N+](=O)[O-])N
PubChem CID	4338370

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	2 / 4
TPSA	97.9 Å²
Synonyms	2-Nitro-1,4-benzenediamine, 1,4-Diamino-2-nitrobenzene, 4-Amino-2-nitroaniline, Fouramine 2R, Ursol Brown RR, 2-Nitro-4-phenylenediamine, 2-Nitro-1,4-phenylenediamine, 1,4-Benzenediamine, 2-nitro-, 2,5-Diaminonitrobenzene, o-Nitro-p-phenylenediamine, Durafur Brown, Zoba Brown RR

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P272, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Nitro-p-phenylenediamine?

The CAS Registry Number of 2-Nitro-p-phenylenediamine is 5307-14-2. It is also known as 2-Nitro-1,4-benzenediamine, 1,4-Diamino-2-nitrobenzene, 4-Amino-2-nitroaniline.

What is the molecular formula and molecular weight of 2-Nitro-p-phenylenediamine?

2-Nitro-p-phenylenediamine has the molecular formula C6H7N3O2 and a molecular weight of 153.14 g/mol. Its IUPAC name is 2-nitrobenzene-1,4-diamine.

What is 2-Nitro-p-phenylenediamine used for?

2-Nitro-p-phenylenediamine is supplied as a characterised reference material related to Retigabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Nitro-p-phenylenediamine can I order?

We supply 2-Nitro-p-phenylenediamine in Reference Standard (70%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Nitro-p-phenylenediamine?

Yes. Every lot of 2-Nitro-p-phenylenediamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Nitro-p-phenylenediamine be shipped internationally?

Yes. 2-Nitro-p-phenylenediamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.