Brigatinib RC 1 (Base)

About Brigatinib RC 1 (Base)

Brigatinib RC 1 (Base) is an impurity of Brigatinib carrying the CAS registry number 53617-36-0. Formula C10H21N3, molecular weight 183.29 g/mol. Its systematic (IUPAC) name is 1-methyl-4-piperidin-4-ylpiperazine. Common synonyms include 1-Methyl-4-(piperidin-4-yl)piperazine and 1-methyl-4-(4-piperidinyl)piperazine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

This Brigatinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Brigatinib RC 1 (Base) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Brigatinib

View every impurity, metabolite and intermediate we list for Brigatinib.

Brigatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Brigatinib RC 1 (Base)
Catalogue No.	VQ-032958
CAS Number	53617-36-0
IUPAC name	1-methyl-4-piperidin-4-ylpiperazine
Molecular formula	C₁₀H₂₁N₃
Molecular weight	183.29 g/mol
Exact mass	183.1735
Grade	Reference Standard
HSN code	38229090
InChIKey	MRYYJGQKVGZGSB-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)C2CCNCC2
PubChem CID	795707

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	1 / 3
TPSA	18.5 Å²
Synonyms	1-Methyl-4-(piperidin-4-yl)piperazine, 1-methyl-4-(4-piperidinyl)piperazine, 1-Methyl-4-(piperidin-4-yl)-piperazine, 1-Methyl-4-piperidin-4-yl-piperazine, 1-methyl-4-(4-piperidyl)piperazine, 4-methyl-1-(4-piperidyl)piperazine, Piperazine, 1-methyl-4-(4-piperidinyl)-, 1-Methyl-4-(4-piperidino)piperazine, CS-M1225, 1-methyl-4-piperidin-4yl-piperazine, 1-methyl-4-piperidin-4-yl-piperazin

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P271, P280, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P319, P321, P332 + P317, P362 + P364, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Brigatinib RC 1 (Base)?

The CAS Registry Number of Brigatinib RC 1 (Base) is 53617-36-0. It is also known as 1-Methyl-4-(piperidin-4-yl)piperazine, 1-methyl-4-(4-piperidinyl)piperazine, 1-Methyl-4-(piperidin-4-yl)-piperazine.

What is the molecular formula and molecular weight of Brigatinib RC 1 (Base)?

Brigatinib RC 1 (Base) has the molecular formula C10H21N3 and a molecular weight of 183.29 g/mol. Its IUPAC name is 1-methyl-4-piperidin-4-ylpiperazine.

What is Brigatinib RC 1 (Base) used for?

Brigatinib RC 1 (Base) is supplied as a characterised reference material related to Brigatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Brigatinib RC 1 (Base) can I order?

We supply Brigatinib RC 1 (Base) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Brigatinib RC 1 (Base)?

Yes. Every lot of Brigatinib RC 1 (Base) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Brigatinib RC 1 (Base) be shipped internationally?

Yes. Brigatinib RC 1 (Base) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.