Domperidone EP Impurity A

Name: Domperidone EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-025362

About Domperidone EP Impurity A

Vaqora Chemicals supplies Domperidone EP Impurity A, a pharmacopeial impurity of Domperidone registered under CAS number 53786-28-0. Its molecular formula is C12H14ClN3O and its molecular weight is 251.71 g/mol. Its systematic (IUPAC) name is 6-chloro-3-piperidin-4-yl-1H-benzimidazol-2-one. Alternative names: Domperidone - Impurity A and 5-Chloro-1-(4-piperidyl)-2-benzimidazolinone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Domperidone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Domperidone EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Domperidone

View every impurity, metabolite and intermediate we list for Domperidone.

Domperidone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Domperidone EP Impurity A
Catalogue No.	VQ-025362
CAS Number	53786-28-0
IUPAC name	6-chloro-3-piperidin-4-yl-1H-benzimidazol-2-one
Molecular formula	C₁₂H₁₄ClN₃O
Molecular weight	251.71 g/mol
Exact mass	251.0825
Grade	Reference Standard
HSN code	38229090
InChIKey	DOAYWDKFDPSTSV-UHFFFAOYSA-N
SMILES	C1CNCCC1N2C3=C(C=C(C=C3)Cl)NC2=O
PubChem CID	104607

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 2
TPSA	44.4 Å²
Synonyms	Domperidone - Impurity A, 5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one, 5-Chloro-1-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, 5-Chloro-1-(4-piperidyl)-2-benzimidazolinone, 5-Chloro-1-piperidin-4-yl-1,3-dihydro-2H-benzimidazol-2-one, 2H-Benzimidazol-2-one, 5-chloro-1,3-dihydro-1-(4-piperidinyl)-, 5-Chloro-1-(4-piperidinyl)-2-benzimidazolinone, 1-(4-Piperidinyl)-1,3-dihydro-5-chlorobenzimidazolone, 5-chloro-1-(piperidin-4-yl)-1,3-dihydro-2h-benzimidazol-2-one, 5-Chloro-1-(4-piperidyl)-1H-benzimidazol-2(3H)-one, 5-chloro-1-(4-piperidyl)-3-hydrobenzimidazol-2-one, 6-chloro-3-(4-piperidyl)-1H-benzimidazol-2-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Domperidone EP Impurity A?

The CAS Registry Number of Domperidone EP Impurity A is 53786-28-0. It is also known as Domperidone - Impurity A, 5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one, 5-Chloro-1-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one.

What is the molecular formula and molecular weight of Domperidone EP Impurity A?

Domperidone EP Impurity A has the molecular formula C12H14ClN3O and a molecular weight of 251.71 g/mol. Its IUPAC name is 6-chloro-3-piperidin-4-yl-1H-benzimidazol-2-one.

What is Domperidone EP Impurity A used for?

Domperidone EP Impurity A is supplied as a characterised reference material related to Domperidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Domperidone EP Impurity A can I order?

We supply Domperidone EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Domperidone EP Impurity A?

Yes. Every lot of Domperidone EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Domperidone EP Impurity A be shipped internationally?

Yes. Domperidone EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.