Cefaclor EP Impurity B

Name: Cefaclor EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-021082

About Cefaclor EP Impurity B

Cefaclor EP Impurity B (CAS 53994-69-7) is a pharmacopeial impurity of Cefaclor offered by Vaqora Chemicals. Formula C7H7ClN2O3S, molecular weight 234.66 g/mol. Systematically, it is named (6R,7R)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Common synonyms include Cefaclor - Impurity B and 7-Amino-3-chlorocephalosporanic Acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Cefaclor impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cefaclor EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cefaclor

View every impurity, metabolite and intermediate we list for Cefaclor.

Cefaclor impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cefaclor EP Impurity B
Catalogue No.	VQ-021082
CAS Number	53994-69-7
IUPAC name	(6R,7R)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular formula	C₇H₇ClN₂O₃S
Molecular weight	234.66 g/mol
Exact mass	233.9866
Grade	Reference Standard
HSN code	38229090
InChIKey	OQSAFIZCBAZPMY-AWFVSMACSA-N
SMILES	C1C(=C(N2[C@H](S1)[C@@H](C2=O)N)C(=O)O)Cl
PubChem CID	6998927

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.8
H-bond donors / acceptors	2 / 5
TPSA	109 Å²
Synonyms	Cefaclor - Impurity B, 7-Amino-3-chlorocephalosporanic Acid, 3-Chloro-7-amino-3-cephem-4-carboxylic Acid, (6R-trans)-7-Amino-3-chloro-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, (6R-trans)-7-amino-3-chloro-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7beta-amino-3-chloro-3-cephem-4-carboxylic acid, (6R,7R)-7-Amino-3-chloro-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-Amino-3-Chloro Cephalosporanic Acid, (6R,7R)-7-Ammonio-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-amino-3-chloro-8-oxo-, (6R,7R)-, (6R,7R)-7-azaniumyl-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, 7-Amino-3-Chloro Cephalosporanic Acid(7-ACCA )

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cefaclor EP Impurity B?

The CAS Registry Number of Cefaclor EP Impurity B is 53994-69-7. It is also known as Cefaclor - Impurity B, 7-Amino-3-chlorocephalosporanic Acid, 3-Chloro-7-amino-3-cephem-4-carboxylic Acid.

What is the molecular formula and molecular weight of Cefaclor EP Impurity B?

Cefaclor EP Impurity B has the molecular formula C7H7ClN2O3S and a molecular weight of 234.66 g/mol. Its IUPAC name is (6R,7R)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

What is Cefaclor EP Impurity B used for?

Cefaclor EP Impurity B is supplied as a characterised reference material related to Cefaclor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cefaclor EP Impurity B can I order?

We supply Cefaclor EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cefaclor EP Impurity B?

Yes. Every lot of Cefaclor EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cefaclor EP Impurity B be shipped internationally?

Yes. Cefaclor EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.